Regulation of intracellular pH, calcium and potassium homeostases in budding yeast
Project goals
The project aims to contribute to the understanding of the role of calcium and potassium homeostases and transport in the regulation of intracellular pH in the model yeast Saccharomyces cerevisiae.
Keywords
Saccharomyces cerevisiaePotassium homeostasisCalcium signallingIntracellular pH
Public support
Provider
Ministry of Education, Youth and Sports
Programme
KONTAKT II
Call for proposals
KONTAKT II 4 (SMSM2014LH4)
Main participants
Fyziologický ústav AV ČR, v. v. i.
Contest type
VS - Public tender
Contract ID
MSMT-9919/2014-1
Alternative language
Project name in Czech
Regulace vnitrobuněčného pH a homeostáze kationtů a vápníku a draslíku v pučících kvasinkách
Annotation in Czech
Cílem projektu je přispět k objasnění úlohy homeostáze a transportu kationtů draslíku a vápníku v regulaci vnitrobuněčného pH a fyziologii buněk modelové kvasinky Saccharomyces cerevisiae.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
EB - Genetics and molecular biology
CEP - secondary branch
EE - Microbiology, virology
CEP - another secondary branch
ED - Physiology
10603 - Genetics and heredity (medical genetics to be 3)
10604 - Reproductive biology (medical aspects to be 3)
10605 - Developmental biology
10606 - Microbiology
10607 - Virology
10608 - Biochemistry and molecular biology
10609 - Biochemical research methods
30101 - Human genetics
30105 - Physiology (including cytology)
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
We have contributed to the elucidation of the interconnection between pH, potassium and calcium homeostases in the yeast Saccharomyces cerevisiae, particularly to the characterization of the role of ESCRT proteins, and Vcx1, Ist2, Kch1, Kch2 and also partly Erv14
Solution timeline
Realization period - beginning
Jul 1, 2014
Realization period - end
Dec 31, 2016
Project status
U - Finished project
Latest support payment
Feb 18, 2016
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP17-MSM-LH-U/01:1
Data delivery date
Jun 23, 2017
Finance
Total approved costs
1,892 thou. CZK
Public financial support
1,892 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK
Basic information
Recognised costs
1 892 CZK thou.
Public support
1 892 CZK thou.
100%
Provider
Ministry of Education, Youth and Sports
CEP
EB - Genetics and molecular biology
Solution period
01. 07. 2014 - 31. 12. 2016