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LL2007

Peptide Killers of Bacteria

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    ERC CZ

  • Call for proposals

    SMSM2020LL002

  • Main participants

    Masarykova univerzita / Středoevropský technologický institut

  • Contest type

    VS - Public tender

  • Contract ID

    MSMT-19250/2020

Alternative language

  • Project name in Czech

    Peptidoví zabijáci bakterií

  • Annotation in Czech

    Vyvineme metodu pro cílení peptidů na membrány se specifickým lipidovým složením a stanovíme klíčové vlastnosti peptidů pro jejich samovolnou translokaci a tvorbu pórů v membránách. Navržené peptidy budou experimentálně testovány na lipidových váčcích, bakteriích a lidských červených krvinkách.

Scientific branches

  • R&D category

    ZV - Basic research

  • OECD FORD - main branch

    10301 - Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

  • OECD FORD - secondary branch

    10610 - Biophysics

  • OECD FORD - another secondary branch

  • CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    BE - Theoretical physics<br>BO - Biophysics

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    In this project, in was deepened the understanding of the interaction between peptides and membranes at the molecular level, which can be further used in the design of more effective antimicrobial peptides. Results of this project were published in 5 papers in prestigious journals.

Solution timeline

  • Realization period - beginning

    Jul 1, 2020

  • Realization period - end

    Dec 31, 2021

  • Project status

    U - Finished project

  • Latest support payment

    Feb 16, 2021

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP22-MSM-LL-U

  • Data delivery date

    Jun 21, 2022

Finance

  • Total approved costs

    13,476 thou. CZK

  • Public financial support

    13,476 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK