The analysis of dynamic and static properties of QT intervals
Public support
Provider
Ministry of Education, Youth and Sports
Programme
KONTAKT
Call for proposals
KONTAKT 7 (SMSM2009ME4)
Main participants
—
Contest type
VS - Public tender
Contract ID
2060/2011-320
Alternative language
Project name in Czech
Analýza dynamických a statických vlastností QT intervalů
Annotation in Czech
Cílem je měření a analýza QT vazby a vyhodnocení nových parametrů této vazby u pacientů s abnormalitami QT. Bude vyhodnoceno, zda nové parametry plně popisují QT fyziologii i u těchto pacientů a budou analyzovány odchylky.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
FA - Cardiovascular diseases including cardio-surgery
CEP - secondary branch
FR - Pharmacology and apothecary chemistry
CEP - another secondary branch
BC - Theory and management systems
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)<br>30104 - Pharmacology and pharmacy<br>30201 - Cardiac and Cardiovascular systems
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
Dynamic model of QT/RR coupling was verified on many ECG. Parameters represent the full set of static and dynamic QT properties. These parameters are genetic (sex, LQT genotype) and excitation specific. Their coupling explains the higher prevalence to arrhythmias in LQT subjects, not looking to value of QTc. Up to now, such explanation does not exists. Possible contribution: drugs tests, diagnosis
Solution timeline
Realization period - beginning
Apr 1, 2009
Realization period - end
Dec 31, 2012
Project status
U - Finished project
Latest support payment
Feb 23, 2012
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP13-MSM-ME-U/01:1
Data delivery date
Jun 28, 2013
Finance
Total approved costs
2,940 thou. CZK
Public financial support
2,940 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK