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NM7604

Mutational status of IgVH genes in chronic lymphocytic leukemia

Public support

  • Provider

    Ministry of Health

  • Programme

    Implementation of molecular biological methods in diagnostics and treatment

  • Call for proposals

    Implementace molekulárně-biologických metod v diagnostice a léčbě 2 (SMZ02003NM)

  • Main participants

    Ústav hematologie a krevní transfúze

  • Contest type

    VS - Public tender

  • Contract ID

Alternative language

  • Project name in Czech

    Mutační stav IgVH genů u pacientů s chronickou lymfatickou leukemií

  • Annotation in Czech

    Zavedení vyšetření mutačního stavu IgVH genů pomůže klinikům v procesu rozhodování o léčbě pacientů s CLL: Výsledky mutačního stavu IgVH genů a jejich prognostický dopad budou korelovány s jinými prognostickými ukazateli.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

    FD - Oncology and haematology

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30204 - Oncology<br>30205 - Hematology

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Detection of mutation status IgVh genes introduced into prognostics of chronic lymphocytic leukemia (CLL).850 pts with CLL,885 IgVh alleles were analyzed.By 337 pts mutation status IgVh genes and Rai clinical stage had most pronounced effect on survival.

Solution timeline

  • Realization period - beginning

    Jan 1, 2003

  • Realization period - end

    Jan 1, 2005

  • Project status

    U - Finished project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP06-MZ0-NM-U/01:1

  • Data delivery date

    Jun 23, 2006

Finance

  • Total approved costs

    1,885 thou. CZK

  • Public financial support

    1,798 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK