Cyclooxygenase-2 polymorphisms and the development of nephropathy in diabetes
Public support
Provider
Ministry of Health
Programme
Departmental Programme of Research and Development - MH II from 2008 to 2011
Call for proposals
VaV pro Ministerstvo zdravotnictví 4 (SMZ02007NR)
Main participants
—
Contest type
VS - Public tender
Contract ID
NR9368-4/2007
Alternative language
Project name in Czech
Polymorfismy genu pro cyklooxygenasu-2 a rozvoj nefropatie při diabetes mellitus.
Annotation in Czech
S využitím molekulárně biologických metodik bude studován polymorfismus -765GC genu COX-2 a jejich možný vliv na monocytární fenotyp COX-2 u diabetiků obou typů s nefropatií ve srovnání s pacienty bez této komplikace a zdravými subjekty.
Scientific branches
R&D category
NV - Nonindustrial research (Applied research excluded Industrial research)
CEP classification - main branch
EB - Genetics and molecular biology
CEP - secondary branch
FD - Oncology and haematology
CEP - another secondary branch
—
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30204 - Oncology<br>30205 - Hematology
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
The study provided new information about distribution of 765G-C genotyps in Czech general population, and lower frequency of the protecitive CC genotypi in DM Type 1 patients. There were no associations of the polymorphism with nephropathy in DM Type 1
Solution timeline
Realization period - beginning
Jan 1, 2007
Realization period - end
Jun 30, 2010
Project status
U - Finished project
Latest support payment
Dec 18, 2009
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP11-MZ0-NS-U/04:2
Data delivery date
Jan 10, 2012
Finance
Total approved costs
3,446 thou. CZK
Public financial support
3,386 thou. CZK
Other public sources
60 thou. CZK
Non public and foreign sources
0 thou. CZK