Radionuclide precursors and radiopharmaceuticals for targeted radionuclide imaging and therapy
Project goals
The proposed project aims to promote development and production of of modern diagnostic and therapeutic radionuclides and radiopharmaceuticals i the Czech Republic.
Keywords
radionuclide precursorsradiopharmaceuticalsradioimmunnotherapypreclinic testing in vitroin vivo
Public support
Provider
Ministry of Education, Youth and Sports
Programme
EUREKA - European co-operation in the sphere of applied and industrial research and development aimed at the support of multinational co-operation among industrial undertakings, research institutes and universities
Call for proposals
EUREKA 6 (SMSM2008OE3)
Main participants
—
Contest type
VS - Public tender
Contract ID
1729/2010-32
Alternative language
Project name in Czech
Radionuklidové prekurzory a radiofarmaka pro cílené radionuklidové zobrazení a terapii v nukleární medicině
Annotation in Czech
Cílem navrhovaného projektu je vývoj technologií pro výrobu nových terapeutických radionuklidů a radiofarmak pro cílenou terapii (radioimunoterapii) na bázi peptidů a monoklonálních protilátek.
Scientific branches
R&D category
AP - Applied research
CEP classification - main branch
FR - Pharmacology and apothecary chemistry
CEP - secondary branch
BG - Nuclear, atomic and molecular physics, accelerators
CEP - another secondary branch
FD - Oncology and haematology
10304 - Nuclear physics
30104 - Pharmacology and pharmacy
30204 - Oncology
30205 - Hematology
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
Among other outputs, the methods for production of Y-90 and Lu-177 radionuclides for therapeutic use in oncology were developed. The most important practical output of the Project was the preparation of a new radioimmunotherapeutic tool, monoclonal antibody Nimotuzumab labeled with Lu-177. The preparation is aimed at treatment of cancers with high expression of epidermal growth factor receptors.
Solution timeline
Realization period - beginning
Jan 1, 2008
Realization period - end
Dec 31, 2011
Project status
U - Finished project
Latest support payment
Mar 2, 2011
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP12-MSM-OE-U/01:1
Data delivery date
Jul 12, 2012
Finance
Total approved costs
21,000 thou. CZK
Public financial support
10,500 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
10,500 thou. CZK
Basic information
Recognised costs
21 000 CZK thou.
Public support
10 500 CZK thou.
50%
Provider
Ministry of Education, Youth and Sports
CEP
FR - Pharmacology and apothecary chemistry
Solution period
01. 01. 2008 - 31. 12. 2011