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5 029 (0,124s) •

Project

Tick microRNAs as modulators of vertebrate host physiology (LUABA22020)

Aim 1: Localization and quantification of miRNAs in Ixodes ricinus ticks Aim 2: Cloning of tick miRNA targets and study of the effect of miRNA on mammalian cells Aim 3: Transcriptomic analysis of host gene modulation up...

Biochemistry and molecular biology

  • 2022 - 2024
    • •
  • 1 199 tis. Kč
    • •
  • 1 199 tis. Kč
    • •
  • MŠMT
Project

Establishment of methodological prerequisites for gene therapy of graft-versus-host disease (NM5898)

Employment of gene therapy methodology to establich conditiona for treating graft-versus-host disease (GvHD).Comparison of efficiency of genetic information transfer into T cells by two different virus vectors.......

FD - Onkologie a hematologie

  • 2000 - 2002
    • •
  • 1 479 tis. Kč
    • •
  • 1 460 tis. Kč
    • •
  • MZ
Project

Functional interaction between host gene regulation and the microbiome in the primate gut (LH15175)

be controlled by host genes with specific immune functions. The project aims at tracing functional interactions between host gene regulation and the microbiome in primates. We will characterize relationships betwe...

EE - Mikrobiologie, virologie

  • 2015 - 2017
    • •
  • 1 997 tis. Kč
    • •
  • 1 997 tis. Kč
    • •
  • MŠMT
Project

Gastric Cryptosporidium of mammals Revealing the mystery of host adaptation and gene regulation during infection (GA21-23773S)

places in the body of the host. While the adaptation of intestinal cryptosporidia has understanding of adaptation this group of parasites to the host with different digestive systems, their gene regulation during life cycl...

Veterinary science

  • 2021 - 2024
    • •
  • 9 726 tis. Kč
    • •
  • 9 726 tis. Kč
    • •
  • GA ČR
Project

The mite as a model for intracellular bacterial interactions Does symbiont war exist for mite hosts? (GF22-15841K)

Intracellular bacteria are known to manipulate the host in different ways to disperse in the host population. We focused on Wolbachia/Spiroplasma and Wolbachia/Cardinium interactions in their mite hosts at the gene...

Microbiology

  • 2022 - 2024
    • •
  • 5 846 tis. Kč
    • •
  • 5 846 tis. Kč
    • •
  • GA ČR
Project

Proteome analysis of the interaction of host cell with intracellular pathogen (7AMB12GR038)

laboratories, for identification of key host cell protein molecules whose quantity ad/or posttranslational modification is modulated by the early phase of host-pathogen interaction of these identified proteins in the h...

EE - Mikrobiologie, virologie

  • 2012 - 2013
    • •
  • 70 tis. Kč
    • •
  • 70 tis. Kč
    • •
  • MŠMT
Project

Understanding the impact of endogenous viruses on host biology a combined computational and experimental strategy (GF22-41060L)

/a technology. By RNA-Seq analyses we will identify affected genes and molecular networks. The identified candidate genes will be modulated by CRISPR in pluripotent stem cellsThe main goal of the project is to shed light on...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2022 - 2025
    • •
  • 3 636 tis. Kč
    • •
  • 3 636 tis. Kč
    • •
  • GA ČR
Project

Comparative parasite hybridisation genomics controlling for host divergence (GA18-19629S)

, further, allow us to identify genes key to host-parasite interaction (e.g. “emergence for examining the mechanisms underlying host-parasite adaptation and specificity. A host allows patterns of parasite genome in...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2018 - 2023
    • •
  • 9 472 tis. Kč
    • •
  • 9 117 tis. Kč
    • •
  • GA ČR
Project

The role of surface proteases in host-parasite interactions (8J19AT036)

are involved in host-parasite interaction and modulate host responses. The main aim different specific host-derived substrates H2: The schistosomal proteases modulate immune responses in their host

Biochemistry and molecular biology

  • 2019 - 2021
    • •
  • 128 tis. Kč
    • •
  • 128 tis. Kč
    • •
  • MŠMT
Project

Host-parasite interactions in hybrid systems of cyprinid fish (GAP505/10/1138)

can rise from species introduction and biological invasion. Until now host (bidirectional gene introgression), Barbus meridionalis and B. barbus (unidirectional gene introgression). The project is aimed to investigate: (1)...

EH - Ekologie – společenstva

  • 2010 - 2014
    • •
  • 3 042 tis. Kč
    • •
  • 3 042 tis. Kč
    • •
  • GA ČR
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