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10 935 (0,087s)

Project

Fabric development during emplacement of volcanic bodies and their dynamics of cooling and fracture formation studied by means of analogue and mathematical modeling. (KJB301110703)

of magneticsusceptibility) analogue modeling.Finite element mathematical modeling will be used as in the analogue models.The second part aims to evaluate fracture patterns developedafter mathematical models. A fie...

DB - Geologie a mineralogie

  • 2007 - 2008
  • 332 tis. Kč
  • 332 tis. Kč
  • AV ČR
Project

Inhibitors of Bacterial RNA Polymerase Based on Nucleotide Analogues (NR9138)

We propose to develop novel inhibitors of bacterial RNA polymerase. Inhibitors will be nucleotide analogues and target its active site.Techniques from molecular biology, organic chemistry, 3D modeling, and high throughput inhibitor ...

EE - Mikrobiologie, virologie

  • 2007 - 2009
  • 9 025 tis. Kč
  • 8 481 tis. Kč
  • MZ
Project

Structure-activity relationship (SAR) study of immunosuppressive effects of pyrimidine analogues (GAP303/12/0172)

The project is aimed at investigation of immunobiological properties of novel pyrimidine analogues. Their immunosuppressive effects will be evaluated by means between the in vitro SAR data and in vivo immunosuppressive effects of the ana...

FR - Farmakologie a lékárnická chemie

  • 2012 - 2016
  • 15 179 tis. Kč
  • 15 179 tis. Kč
  • GA ČR
Project

Towards a true 8-digit digitiser (9B23020)

The overall objective of the project is to perform bottom-up development and research underpinning the development of a digitiser featuring state-of-the-art performance, whose performance exceeds that of currently available digital multimeters (DMMs)...

Electrical and electronic engineering

  • 2023 - 2026
  • 3 174 tis. Kč
  • 1 586 tis. Kč
  • MŠMT
Project

New purine nucleoside analogues for therapeutic applications (OC D13.20)

Synthesis of purine nucleosides, heir acyclic analogues and analogues of nucleotides substituted by C=alkyl, aryl and cycloalkyl substituents as purinoceptor modulators.......

CC - Organická chemie

  • 2001 - 2003
  • 2 662 tis. Kč
  • 1 335 tis. Kč
  • MŠMT
Project

New purine nucleoside analogues for therapeutic applications (1P04OCD13.20)

Synthesis of purine nucleosides, heir acyclic analogues and analogues of nucleotides substituted by C=alkyl, aryl and cycloalkyl substituents as purinoceptor modulators.......

FR - Farmakologie a lékárnická chemie

  • 2004 - 2004
  • 891 tis. Kč
  • 400 tis. Kč
  • MŠMT
Project

Preparation of taxol and its analoques. (PZ-CH/33)

Development a procedure for small-scale production of taxanol its analogues. Preparation of a new taxol analogues....

FR - Farmakologie a lékárnická chemie

  • 1997 - 2001
  • 15 216 tis. Kč
  • 7 716 tis. Kč
  • MH
Project

Testability of analogue and analogue- digital integrated circuits (GA102/95/0875)

JB - Senzory, čidla, měření a regulace

  • 1995 - 1997
  • 2 524 tis. Kč
  • 2 524 tis. Kč
  • GA ČR
Project

Analogues of insulin, IGF-1 and IGF-2 to study their neuroprotective effects in neurons and glial cells. (GA22-17978S)

analogues with significantly altered receptor binding properties and compare them to effects of the native hormones in model neurons and glial cells. The study should respond to emerging questions whether the use of specific hormon...

Cell biology

  • 2022 - 2024
  • 9 928 tis. Kč
  • 9 017 tis. Kč
  • GA ČR
Project

Human insulin and its analogues Semisynthetic approache. (PZ-Z2/32)

Biological and physiochemical evaluation of human insulin intermediates. Design and preparation of selected human insulin analogue isolation and physiochemical and biological evaluatio.......

FR - Farmakologie a lékárnická chemie

  • 1997 - 2000
  • 11 044 tis. Kč
  • 4 991 tis. Kč
  • MH
  • 1 - 10 out of 10 935