All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Filters

122 (0,072s)

Project

Role of cytochrome P450 in biodegradation of dyes and triazines by white rot fungi (1P05ME827)

mechanism of degradation of xenobiotics focused on systems containing p450 cytochrom, used by white rot fungi...

EE - Mikrobiologie, virologie

  • 2005 - 2005
  • 205 tis. Kč
  • 87 tis. Kč
  • MŠMT
Project

Expression of Human Cytochrome P450 2A6 in Bacteria (IZ3505)

FM - Hygiena

  • 1996 - 1998
  • 2 097 tis. Kč
  • 2 097 tis. Kč
  • MZ
Project

The role of interaction of cytochrome P-450 metabolites and the renin-angiotensin system in the control of renal function (NR8271)

The role of interaction of cytochrome P-450 metabolites and the renin-angiotensin system in the control of renal function and development of angiotensin II-dependent hypertension will be studied.......

FP - Ostatní lékařské obory

  • 2005 - 2007
  • 4 904 tis. Kč
  • 4 773 tis. Kč
  • MZ
Project

Expression of cytochromes P450 in hematopoietic stem cells. (NL7295)

Expression of cytochromes P450 in hematopoietic stem cells obtained by separetion from petipheral blood will be follewed by Northern blogging, real-time PCR, Western blotting and by determination of specific enzyme activities.......

FR - Farmakologie a lékárnická chemie

  • 2002 - 2004
  • 1 528 tis. Kč
  • 1 212 tis. Kč
  • MZ
Project

Pig enzymes of biotransformation (1P05OC050)

recognition of proteins, enzymes contributing to transformations (biotransformations) of substances - cytochromes P450 and other enzymes of transformation of foreign substances......

EB - Genetika a molekulární biologie

  • 2005 - 2008
  • 2 138 tis. Kč
  • 1 443 tis. Kč
  • MŠMT
Project

Effect of genotype,cytochrome P450 induction and inhibition on the metabolism and action of industrial chemicals and drugs. (IZ2763)

FM - Hygiena

  • 1995 - 1998
  • 2 343 tis. Kč
  • 2 343 tis. Kč
  • MZ
Project

Mechanism of modulation of cytochrome P450 1A1/2 mediated oxidation of drugs and carcinogens by cytochrome b5; experimental and computational approach (GA203/09/0812)

Cytochromes P450 (CYPs) represent a large and important group of enzymes oxidizing majority of drugs and carcinogens. Eukaryotic CYPs act in tight cooperation with other proteins in the membrane of endoplasmic reticulum. One of them, cyt...

CE - Biochemie

  • 2009 - 2011
  • 1 349 tis. Kč
  • 1 349 tis. Kč
  • GA ČR
Project

Cytochrome P450 active sites (OC 133)

study of compresibility and flexibility of active sites of P450 cytocromes, forms CYP2C9 and CYP3A4...

CE - Biochemie

  • 2006 - 2007
  • 1 180 tis. Kč
  • 800 tis. Kč
  • MŠMT
Project

Pharmacological blockade of cytochrome P450 pathway as a new approach in hypertension treatment (NT11230)

The role of epoxyeicotrienoic acids in the pathophysiology of ANG II-dependent form of hypertension will be studied....

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2010 - 2013
  • 5 724 tis. Kč
  • 5 724 tis. Kč
  • MZ
Project

Modeling drug-drug interactions in vivo using in vitro methods (OC B15.30)

Identification of human cytochrome P450 isozymes involved in the metabolism of memantine and amiodarone. Quantification of inhibitory action of memantine towards human cytochorome P450 isozymes.......

FR - Farmakologie a lékárnická chemie

  • 2000 - 2003
  • 4 512 tis. Kč
  • 2 975 tis. Kč
  • MŠMT
  • 1 - 10 out of 122