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24 (0,059s) •

Project

Spermatogenesis impairment in the rats carrying the mutant allele hd analysis of molecular function of both normal and mutant allele of the LOC303240 (GP301/07/P178)

into the molecular mechanisms underlying impairment of spermatogenesis and resulting male the function of wild-type LOC303240 allele in the regulation of spermatogenesis by means of spermatogenesis, and perhaps even with p...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 1 440 tis. Kč
    • •
  • 1 440 tis. Kč
    • •
  • GA ČR
Project

Gene expression profiling during mouse spermatogenesis Implications for meiotic sex chromosome inactivation and gene retroduplication (GA301/07/1383)

Mouse spermatogenesis and meiotic sex chromosome inactivation (MSCI) will be dissected by genome wide expression profiles acquired using DNA microarrays. We will determine gene expression profiles of two strains C57BL/6J and PWD/Ph for three...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 2 472 tis. Kč
    • •
  • 2 472 tis. Kč
    • •
  • GA ČR
Project

The influence of TSPY gene sequence, repetition and expression variability on biological function in normal and pathological cells. (NR7821)

The project is mainly aimed on testing of correlation between varieties of TSPY genes and germinal tumor and gonadoblastoma development. Also study the influence of types of the TSPY genes on spermatogenesis.......

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 2 760 tis. Kč
    • •
  • 2 752 tis. Kč
    • •
  • MZ
Project

Epigenetic regulators of gene expression in mouse spermatogenesis (GPP305/11/P630)

In our laboratory, have identified hybrid sterility gene Prdm9, which is crucial for the epigenetic regulation of expression during mouse spermatogenesis. In a search for genes, which have a similar mRNA expression pattern as Prdm9, genes en...

EB - Genetika a molekulární biologie

  • 2011 - 2013
    • •
  • 2 957 tis. Kč
    • •
  • 2 957 tis. Kč
    • •
  • GA ČR
Project

Spermatogonial stem cells in the process of chicken spermatogenesis (ME 908)

To develop a joined project of experimental transgenesis in domestic fowl based on better understanding of gene expression during chicken spermatogenesis, identification of unique surface molecular markers of testicular spermatogonial cells ...

EB - Genetika a molekulární biologie

  • 2007 - 2011
    • •
  • 2 128 tis. Kč
    • •
  • 2 128 tis. Kč
    • •
  • MŠMT
Project

Effect of DNA copy number variation on fertility of the house mouse (GA16-19158S)

also discovered that spermatogenesis of the semisterile mice is affected by copy...

EB - Genetika a molekulární biologie

  • 2016 - 2020
    • •
  • 4 979 tis. Kč
    • •
  • 4 733 tis. Kč
    • •
  • GA ČR
Project

The impact of selected endocrine disruptors on human spermatogenesis (NT13369)

Endocrine disruptor (ED) is defined as an exogenous substance interfering with the synthesis, secretion, transport, binding or action of natural hormones responsible for reproduction, development and/or behavior. The project aspires to increase the k...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2012 - 2015
    • •
  • 6 204 tis. Kč
    • •
  • 6 204 tis. Kč
    • •
  • MZ
Project

Effect of Estrogens on Testicular/Sperm Epigenome and Early Embryonic Development (GJ20-17403Y)

, the epigenetic effect of estrogens on the process of spermatogenesis and its physiological...

Genetics and heredity (medical genetics to be 3)

  • 2020 - 2022
    • •
  • 6 910 tis. Kč
    • •
  • 6 910 tis. Kč
    • •
  • GA ČR
Project

Molecular biological aspects of the sperm head-tail coupling apparatus in normal and hd mutant rats (ME10034)

development, there is need to understand the highly complex biology of spermatogenesis...

EB - Genetika a molekulární biologie

  • 2010 - 2012
    • •
  • 1 800 tis. Kč
    • •
  • 1 800 tis. Kč
    • •
  • MŠMT
Project

3D in situ molecular analysis of the reproductive processes in the natural and pathological states (GA23-06591S)

in the frame of our own goals to study the process of spermatogenesis with emphasis...

Reproductive biology (medical aspects to be 3)

  • 2023 - 2025
    • •
  • 9 282 tis. Kč
    • •
  • 9 282 tis. Kč
    • •
  • GA ČR
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