The influence of TSPY gene sequence, repetition and expression variability on biological function in normal and pathological cells.
Public support
Provider
Ministry of Health
Programme
Branch programm of research of the Ministry of Health
Call for proposals
VaV pro Ministerstvo zdravotnictví 1 (SMZ02004NR)
Main participants
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Contest type
VS - Public tender
Contract ID
—
Alternative language
Project name in Czech
Vliv sekvenční, repetiční a expresní variability genu TSPY na biologickou funkci v normálních a patologických buňkách.
Annotation in Czech
Projekt je zaměřen především na testování korelace mezi zastoupením variant TSPY genů a rozvojem germinálního tumoru a gonadoblastomu a na vliv variant genů TSPY na spermatogenezi.
Scientific branches
R&D category
NV - Nonindustrial research (Applied research excluded Industrial research)
CEP classification - main branch
EB - Genetics and molecular biology
CEP - secondary branch
FD - Oncology and haematology
CEP - another secondary branch
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OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30204 - Oncology<br>30205 - Hematology
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Authors elaborated methods for investigation of repetion and sequential variability of TSP-Y encoded gene. They demostrated the significance of these methods for detection of male infertibility and recognition of malignant and healthy tissuue.
Solution timeline
Realization period - beginning
Jan 1, 2004
Realization period - end
Jan 1, 2006
Project status
U - Finished project
Latest support payment
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Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP07-MZ0-NR-U/06:2
Data delivery date
Aug 8, 2007
Finance
Total approved costs
2,760 thou. CZK
Public financial support
2,752 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
1 thou. CZK