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9 (0,105s) •

Project

Characteristics and consequences of genetic variants associated with hyperuricemia, gout progression, disease onset, and treatment effects a perspective on an early diagnosis and individualized (NU22-01-00465)

Gout is the most common form of inflammatory arthritis with increasing incidence and prevalence, including early-onset < 40 years of age. Gout has-third to one-half of gout patients receive curative urate-lowering treatment...

Rheumatology

  • 2022 - 2025
    • •
  • 8 293 tis. Kč
    • •
  • 8 293 tis. Kč
    • •
  • MZ
Project

Function study of allelic variants of urate transporters in primary hyperuricemia and gout (NV15-26693A)

concentration in a group of 300 Czech individuals (150 primary hyperuricemia/gout, 150 the molecular base of primary hyperuricemia/gout. Our project will help to clear of primary hyperuricemia/gout.......

FP - Ostatní lékařské obory

  • 2015 - 2019
    • •
  • 9 818 tis. Kč
    • •
  • 9 818 tis. Kč
    • •
  • MZ
Project

Molecular basis of familial juvenile hyperuricemic nephropathy (NE7046)

to pathogenesis of primary gout. Project is based on application and development of modern...

EB - Genetika a molekulární biologie

  • 2002 - 2004
    • •
  • 7 179 tis. Kč
    • •
  • 7 174 tis. Kč
    • •
  • MZ
Project

Purine content in meat alternatives evaluation of risks and possibilities in reducing their impact on hyperuricemia (GP525/08/P503)

Development of gout is greatly influenced by high intake of dietary purines of which hypoxanthine and adenine are exhibiting highest uricogenic potential, leading in some cases to hyperuricemia, deposition of ureate in joint fluids lead to t...

GM - Potravinářství

  • 2008 - 2010
    • •
  • 994 tis. Kč
    • •
  • 994 tis. Kč
    • •
  • GA ČR
Project

Familial juvenile gouty nefropathy gene mapping and identification. (NM27)

The aim of the project is to identify a gene responsible for autosomal dominant form of gout-familial juvenile gouty nepropathy.As a candidate not yet identified human urate transporter is suggested. As a parallel aproach,linkage analysis in...

EB - Genetika a molekulární biologie

  • 1998 - 2000
    • •
  • 4 270 tis. Kč
    • •
  • 4 270 tis. Kč
    • •
  • MZ
Project

Diffuse idiopathic skeletal hyperostosis genetic factors, skeletal metabolism, differencial diagnosis (GA311/98/1585)

. It is supposed that DISH represents a metabolic disorder with relations to obesity, gout...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1998 - 2000
    • •
  • 2 509 tis. Kč
    • •
  • 2 509 tis. Kč
    • •
  • GA ČR
Project

European structure for coordination of research and diagnosis of inherited purine and pyrimidine disorders (OK 352)

)To set up diagnostic procedure for gout and hypouricemia,d)To diagnose new patients,e...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1998 - 2001
    • •
  • 1 450 tis. Kč
    • •
  • 1 400 tis. Kč
    • •
  • MŠMT
Project

Effect of Breast Morphology on Lactaction Onset (8J18FR014)

partner laboratory at the Centre des Sciences du Gout et de l´Alimentation...

Zoology

  • 2018 - 2019
    • •
  • 88 tis. Kč
    • •
  • 88 tis. Kč
    • •
  • MŠMT
Project

Identification and characterization of genetic factors and pathogenetic mechanism of defects affecting de novo purine metabolism (NU23-01-00500)

of purine metabolism are wide-ranging and include rheumatologic (gout...

Biochemistry and molecular biology

  • 2023 - 2026
    • •
  • 9 637 tis. Kč
    • •
  • 9 637 tis. Kč
    • •
  • MZ
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