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13 (0,07s)

Project

Ectopic release of glycine - physiological role and mechanism (GAP303/11/0131)

(SOC). The endogenous sources of glycine in the SOC were not fully elucidated yet. We propose to study mechanisms of glycine ectopic release inthe rat medial and molecular biology methods. We will study the somatodendritic release ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2015
  • 3 079 tis. Kč
  • 3 079 tis. Kč
  • GA ČR
Project

The Study of Glycine Site at the NMDA Receptor in the Brain by Biochemical and Behavioral Methods Using Newly Syntesized Agents (GA307/93/2183)

FR - Farmakologie a lékárnická chemie

  • 1993 - 1995
  • 560 tis. Kč
  • 1 120 tis. Kč
  • GA ČR
Project

Genetic engineering and molecular biology in grain legumes (ME 433)

The aim of the project is the development of efficient methodology of genetic transformation mediated by Agrobacterium or via particle bombardment technology in pea (Pisum sativum L.) and soybean (Glycine max (L.) Merr.). The technology will...

GE - Šlechtění rostlin

  • 2001 - 2003
  • 2 120 tis. Kč
  • 755 tis. Kč
  • MŠMT
Project

Developmental plasticity of GABA- and glycinergic systems in the rat medial nucleus of the trapezoid body (GA309/03/1158)

functional GABAA and glycine receptors that when activated enhance glutamate release from with immunohistochemical detection of GABA, glycine and their receptors. Our research is also aimed......

ED - Fyziologie

  • 2003 - 2005
  • 2 329 tis. Kč
  • 2 329 tis. Kč
  • GA ČR
Project

Measurement of genetic stability / instability of pea and soybean somaclones by molecular techniques (ME 211)

Molecular characterization (protein and DNA level) of pea and soybean somaclones produced by direct and indirect somatic embryogenesis in relation to genetic stability / variability. Understanding the mechanisms leading to genetically stable or unsta...

EI - Biotechnologie a bionika

  • 1998 - 1999
  • 750 tis. Kč
  • 400 tis. Kč
  • MŠMT
Project

Functions and membrane properties of glial cells in the rat spinal cord slices (GA309/96/0881)

, glycine, substance P, glutamate, NMDA, AMPA and kainate during cell swelling...

ED - Fyziologie

  • 1996 - 1998
  • 1 368 tis. Kč
  • 1 368 tis. Kč
  • GA ČR
Project

Heterotrophic growth of chromerid algae metabolic adaptation to growth without access to light. (GA25-15611S)

for more than three years in the absence of light with glycine as a carbon source. Our...

Plant sciences, botany

  • 2025 - 2027
  • 10 422 tis. Kč
  • 10 422 tis. Kč
  • GA ČR
Project

Application of proline rich sequences in biologically active peptides (GA203/00/0955)

We suggest to study peptide sequences rich of proline and of its derivative residues (hydroxyproline, 3(4)- alkylprolines, dehydroproline) as a potential factor instigating in peptide hormones activity of hormonogenes. Contrary to oligomeres of g...

CC - Organická chemie

  • 2000 - 2002
  • 2 082 tis. Kč
  • 1 570 tis. Kč
  • GA ČR
Project

The role of spinal inhibitory neurons in the development of painful states. (GA20-19136S)

Chronic and neuropathic pain conditions are often characterized by attacks of spontaneous pain and allodynia. The treatments available are not effective and accompanied by serious side effects. In order to develop new effective analgesic treatments, ...

Neurosciences (including psychophysiology)

  • 2020 - 2022
  • 6 209 tis. Kč
  • 6 209 tis. Kč
  • GA ČR
Project

The role of GABA-B receptors in the mammalian MNTB (GA309/06/1304)

GABAB receptors (GABABRs) modulate synaptic transmission by controlling neurotransmitter release and by inducing postsynaptic hyperpolarization. At many central synapses GABABRs localize to either side of the junction. The individual contributions of...

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2008
  • 2 610 tis. Kč
  • 2 610 tis. Kč
  • GA ČR
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