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Projects

4 968 projects (0,118s) •

Project

Resistance to antibiotics and new derivatives of antibiotics for medical purposes. (PZ-Z2/23)

New or modified antibiotics with improved physico-chemical properties and therapeutic effects. Development of new derivates of lincosamine antibiotics by means of gene engineering or biotransformation.......

FR - Farmakologie a lékárnická chemie

  • 1997 - 2001
    • •
  • 28 602 tis. Kč
    • •
  • 11 300 tis. Kč
    • •
  • MH
Project

Development of molecular-genetic markers for modern breeding and gene engineering of hop (Humulus lupulus) based on the system of genomic and expression libraries. (QH81052)

The project aims to develop molecular-genetic markers for modern selection and breeding programmes and genetic engineering of hop (Humulus lupulus). In the project on generalselection of markers is replaced by the system that is targeted to ...

EB - Genetika a molekulární biologie

  • 2008 - 2012
    • •
  • 5 180 tis. Kč
    • •
  • 4 920 tis. Kč
    • •
  • MZe
Project

Targeting DNA repair genes in engineered human cancer cells deficient in BRCA2, FANCC and FANCG (KJB502030901)

Fanconi anemia (FA) genes BRCA2, FANCC and FANCG are inactivated in a variety recombination (HR). Nucleotide excision repair (NER) genes including translesional cross-links. Furthermore, in absence of these genes, stalled r...

EB - Genetika a molekulární biologie

  • 2009 - 2010
    • •
  • 679 tis. Kč
    • •
  • 679 tis. Kč
    • •
  • AV ČR
Project

Molecular basis of osmotolerant yeast Z. rouxii, Z. bailii and D. hansenii specific properties and their biotechnological applications (GAP503/10/0307)

) isolation of new genes involved in fructose, glycerol and alkali-metal-cation transport for genome engineering of Z. bailii and D. hansenii, and (3) construction and phenotypic by heterologous (over)expression of the isolated ...

EI - Biotechnologie a bionika

  • 2010 - 2014
    • •
  • 5 551 tis. Kč
    • •
  • 5 351 tis. Kč
    • •
  • GA ČR
Project

Phytotoxicity of nanofibres (LD14125)

Project aim is to explore the impact of nanofibres on developmental and growth processes in plants. The project should answer the question concerning toxicity of nanofibres for plants and help to estimate environmental risks of engineered na...

DN - Vliv životního prostředí na zdraví

  • 2014 - 2017
    • •
  • 2 227 tis. Kč
    • •
  • 2 227 tis. Kč
    • •
  • MŠMT
Project

*Biotechnological production of antigens of Borrelia burgdorferi sensu lato for preparation of prototype of vaccine against Lyme borreliosis. (FD-K3/100)

*Research and development of the biotechnological procedure on the level of gene engineering pointed to preparation of protein unites suitable for basic prototype formula of subunit vaccine against Lyme borreliosis.......

EI - Biotechnologie a bionika

  • 2003 - 2005
    • •
  • 31 871 tis. Kč
    • •
  • 11 991 tis. Kč
    • •
  • MPO
Project

Center of Excellence in Regenerative Medicine (EH22_008/0004562)

work packages in the field of regeneration and tissue engineering. WP1 will develop and nanomaterials. WP3 will elaborate methodologies crucial for cell and gene therapy of retinal and vascular patches using tissue engineering<...

Neurosciences (including psychophysiology)

  • 2023 - 2028
    • •
  • 481 225 tis. Kč
    • •
  • 121 750 tis. Kč
    • •
  • MŠMT
Project

Czech Centre for Phenogenomics (LM2018126)

to the biological and medical research community studying gene function. An understanding of gene function is essential as population-based genetic associations using genome treatment if the identified genes are ascribed b...

Genetics and heredity (medical genetics to be 3)

  • 2020 - 2022
    • •
  • 278 586 tis. Kč
    • •
  • 278 586 tis. Kč
    • •
  • MŠMT
Project

Zoom in the fish eye & blood molecular evolution of functional adaptations in the deep-sea and freshwater fishes (GA21-31712S)

fix mutations in the coding sequence of the rhodopsin gene leading engineering to regenerate and measure exact function of distinct deep-sea rhodopsins will also employ the in vitro protein-engineering approach to function...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2021 - 2024
    • •
  • 9 953 tis. Kč
    • •
  • 9 953 tis. Kč
    • •
  • GA ČR
Project

Mechanisms of toxicity of gasoline engine emissions in 3D tissue cultures and a model bronchial epithelial cell line (GA18-04719S)

. Gasoline engine exhaust has been classified as possibly carcinogenic to humans injection spark ignition engines powered by gasoline and an alternative fuel will be tested. Chemical analysis of complete engine exhaust and ...

Biochemistry and molecular biology

  • 2018 - 2022
    • •
  • 7 878 tis. Kč
    • •
  • 7 707 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 4 968