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Projects

95 projects (0,094s) •

Project

Effects of non-invasive brain stimulation on hypokinetic dysarthria, micrographia, and brain plasticity in patients with Parkinson's disease (NV16-30805A)

Hypokinetic dysarthria (HD) is common in Parkinson’s disease (PD) patients and it responds only partially to pharmacotherapy and surgery of PD. We will explore short-term effects of repetitive transcranial magnetic stimulation (rTMS) applied over pre...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2019
    • •
  • 10 796 tis. Kč
    • •
  • 10 796 tis. Kč
    • •
  • MZ
Project

Transcranial magnetic stimulation in the treatment of bipolar depression (NV16-31380A)

Four-week, randomized, sham-controlled, double-blind, parallel study to evaluate the efficacy of high-frequency MRI-guided repetetive transcranial magnetic stimulation (rTMS) targeted to two different brain areas in bipolar I depression with the cons...

FL - Psychiatrie, sexuologie

  • 2016 - 2020
    • •
  • 6 383 tis. Kč
    • •
  • 6 058 tis. Kč
    • •
  • MZ
Project

Changes of sensorimotor system organization and activation following botulinum toxin injection in cervical dystonia patients (NV16-30210A)

Patients suffering from cervical dystonia (CD) are very often notably limited in working and social activities. Botulinum toxin (BoNT-A) is currently considered to be the one of the most effective therapeutic options. However, the complete mechanism ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2019
    • •
  • 6 726 tis. Kč
    • •
  • 6 726 tis. Kč
    • •
  • MZ
Project

Dorsomedial prefrontal cortex repetitive transcranial magnetic stimulation (dmPFC-rTMS) in the augmentation of antidepressants (DOPRERA study). Efficacy, tolerability and neurophysiological changes. (NU22-04-00192)

Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for depression but the optimal method of administration has yet to be determined and various modifications of rTMS are available. The aim of the project is to compare the e...

Psychiatry

  • 2022 - 2025
    • •
  • 9 365 tis. Kč
    • •
  • 9 365 tis. Kč
    • •
  • MZ
Project

Impulsivity phenotypes and their clinical impact in neuropsychiatric disorders (NV15-30062A)

Impulsivity is an important feature that accompanies many neuropsychiatric disorders and complicates their course and treatment. In contrast to its frequent manifestation and impact, relatively little is known about its neurobiology. Moreover, there ...

FL - Psychiatrie, sexuologie

  • 2015 - 2018
    • •
  • 10 519 tis. Kč
    • •
  • 9 911 tis. Kč
    • •
  • MZ
Project

The efficacy of transcranial direct current stimulation (tDCS) in the treatment of depression and brain functional changes compared to venlafaxine. (NV15-29900A)

The main goal of 4-week, double-blind and subsequent 8-week, open-label studies is to compare efficacy and tolerability of transcranial direct current stimulation and venlafaxine in the acute treatment of depression and relapse prevention. Next aims ...

FL - Psychiatrie, sexuologie

  • 2015 - 2019
    • •
  • 9 562 tis. Kč
    • •
  • 9 562 tis. Kč
    • •
  • MZ
Project

Diagnostics and Therapy of Orofacial Pain (NV15-31538A)

The main objective of the project is to improve the diagnosis and options of orofacial pain (OB) treatment using transcranial stimulation (TS). Within the project the unique objective non-invasive non-contact thermal imaging of the affected area in t...

FH - Neurologie, neurochirurgie, neurovědy

  • 2015 - 2018
    • •
  • 11 990 tis. Kč
    • •
  • 11 915 tis. Kč
    • •
  • MZ
Project

rTMS-enhanced psychotherapy for borderline personality disorder (NU23-04-00472)

Borderline personality disorder (BPD) is a devastating pervasive mental disorder characterized by emotion regulation impairment and marked impulsive behavior, including self-harming and suicidal behavior. 40 % to 85 % of patients with BPD attempt to ...

Neurosciences (including psychophysiology)

  • 2023 - 2026
    • •
  • 12 534 tis. Kč
    • •
  • 12 534 tis. Kč
    • •
  • MZ
Project

Implication of cognitive reserve in non-pharmacological intervention outcomes (NU21-04-00652)

Cognitive reserve (CR) can be defined as a gradual accumulation of neural resources and their adaptability (i.e. efficiency, capacity, flexibility) due to genetic and/or life-long environmental factors, that mitigate cognitive effects of age-related ...

Neurosciences (including psychophysiology)

  • 2021 - 2025
    • •
  • 9 440 tis. Kč
    • •
  • 9 440 tis. Kč
    • •
  • MZ
Project

Improving the quality of life in patients with stable maculopathy by implanting intraocular macula lenses and modulating visual plasticity by transcranial electrical stimulation (NV18-06-00484)

A sight loss is the most severe manifestation of the visual organ failure and it causes severity-dependent decrement in quality of life comparable to heart diseases or cancer. Macular degenerations are leading cause of legal blindness in the develope...

Otorhinolaryngology

  • 2018 - 2022
    • •
  • 7 863 tis. Kč
    • •
  • 7 863 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 95