Croatian national reference Y-STR haplotype database

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00007064%3AK01__%2F12%3AN0000001" target="_blank" >RIV/00007064:K01__/12:N0000001 - isvavai.cz</a>

Result on the web

<a href="https://link.springer.com/article/10.1007/s11033-012-1610-3" target="_blank" >https://link.springer.com/article/10.1007/s11033-012-1610-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11033-012-1610-3" target="_blank" >10.1007/s11033-012-1610-3</a>

Result language

angličtina

Original language name

Croatian national reference Y-STR haplotype database

Original language description

A reference Y-chromosome short tandem repeat (STR) haplotype database is needed for Y-STR match interpretation as well as for national and regional characterization of populations. The aim of this study was to create a comprehensive Y-STR haplotype database of the Croatian contemporary population and to analyze substructure between the five Croatian regions. We carried out a statistical analysis of the data from previously performed genetic analyses collected during routine forensic work by the Forensic Science Centre "Ivan Vučetić". A total of 1,100 unrelated men from eastern, western, northern, southern and central Croatia were selected for the purpose of this study. Y-STRs were typed using the AmpFISTR Yfiler PCR amplification kit. Analysis of molecular variance calculated with the Y chromosome haplotype reference database online analysis tool included 16 population samples with 20,247 haplotypes. A total of 947 haplotypes were recorded, 848 of which were unique (89.5%). Haplotype diversity was 0.998, with the most frequent haplotype found in 9 of 1,100 men (0.82%). Locus diversity varied from 0.266 for DYS392 to 0.868 for DYS385. Discrimination capacity was 86.1%. Our results suggested high level of similarity among regional subpopulations within Croatia, except for mildly different southern Croatia. Relative resemblance was found with Bosnia and Herzegovina and Serbia. Whit Atheys' Haplogroup Predictor was used to estimate the frequencies of Y-chromosome haplogroups. I2a, R1a, E1b1b and R1b haplogroups were most frequent in all Croatian regions. These results are important in forensics and contribute to the population genetics and genetic background of the contemporary Croatian population.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/VG20122015071" target="_blank" >VG20122015071: Development, Application and Automation of Genetic Analysis Technologies and Procedures Aimed at Predicting and Identifying Perpetrators and Victims of Terrorist Attacks, Crimes nad Natural Disasters.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecular Biology Reports

ISSN

1573-4978

e-ISSN

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Volume of the periodical

39

Issue of the periodical within the volume

7

Country of publishing house

DE - GERMANY

Number of pages

15

Pages from-to

7727–7741

UT code for WoS article

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EID of the result in the Scopus database

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