A global analysis of Y-chromosomal haplotype diversity for 23 STR loci

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00007064%3AK01__%2F14%3AN0000002" target="_blank" >RIV/00007064:K01__/14:N0000002 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.fsigen.2014.04.00" target="_blank" >http://dx.doi.org/10.1016/j.fsigen.2014.04.00</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.fsigen.2014.04.008" target="_blank" >10.1016/j.fsigen.2014.04.008</a>

Result language
angličtina
Original language name
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci
Original language description
In a worldwide collaborative effort, 19,630 Y-chromosomes were sampled from 129 different populations in 51 countries. These chromosomes were typed for 23 short-tandem repeat (STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385ab, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, GATAH4, DYS481, DYS533, DYS549, DYS570, DYS576, and DYS643) and using the PowerPlex Y23 System (PPY23, Promega Corporation, Madison, WI). Locus-specific allelic spectra of these markers were determined and a consistently high level of allelic diversity was observed. A considerable number of null, duplicate and off-ladder alleles were revealed. Standard single-locus and haplotype-based parameters were calculated and compared between subsets of Y-STR markers established for forensic casework. The PPY23 marker set provides substantially stronger discriminatory power than other available kits but at the same time reveals the same general patterns of population structure as other marker sets. A strong correlation was observed between the number of Y-STRs included in a marker set and some of the forensic parameters under study. Interestingly a weak but consistent trend toward smaller genetic distances resulting from larger numbers of markers became apparent.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
<a href="/en/project/VG20122015071" target="_blank" >VG20122015071: Development, Application and Automation of Genetic Analysis Technologies and Procedures Aimed at Predicting and Identifying Perpetrators and Victims of Terrorist Attacks, Crimes nad Natural Disasters.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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