Antimicrobial polyhydroxybutyrate submicron fiber mat loaded with extract of Hypericum perforatum

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00013251%3A_____%2F22%3AN0000003" target="_blank" >RIV/00013251:_____/22:N0000003 - isvavai.cz</a>
Alternative codes found
RIV/28778758:_____/22:N0000021 RIV/00027022:_____/22:N0000071
Result on the web
<a href="http://www.kspbtjpb.org/journal/view.html?doi=10.5010/JPB.2022.49.3.257" target="_blank" >http://www.kspbtjpb.org/journal/view.html?doi=10.5010/JPB.2022.49.3.257</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5010/JPB.2022.49.3.257" target="_blank" >10.5010/JPB.2022.49.3.257</a>

Result language
angličtina
Original language name
Antimicrobial polyhydroxybutyrate submicron fiber mat loaded with extract of Hypericum perforatum
Original language description
The aim of this work was to prepare a new biodegradable polyhydroxybutyrate submicron fiber mat loaded with Hypericum perforatum hypericin rich raw extract by centrifugal spinning technology, an alternative approach to fabricate nanofibers or microfibers from solutions at high speed and low cost. Hypericins in methanol/acetone extract of H. perforatum were determined by UHPLC-MS/MS and HPLC/PDA methods. Pure PHB and the H. perforatum extract enriched PHB submicron fiber mats were prepared using a pilot plant demonstrator for the centrifugal spinning technology and characterized by SEM. Singlet oxygen production was quantified by the 1,3-diphenylisobenzofuran method in hexane. The results proved a significant production of singlet oxygen by the prepared submicron fiber mat. We have also found a very significant antibacterial activity against Escherichia coli CCM 5417 bacterial strain by a method in accordance with JIS Z 2801 / ISO 22196 tests. The H. perforatum extract enriched PHB submicron fiber mats showed potential in development of self-cleaning and antimicrobial air filters.
Czech name
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Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
20503 - Textiles; including synthetic dyes, colours, fibres (nanoscale materials to be 2.10; biomaterials to be 2.9)

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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