Lipid metabolism in renal transplant patients receiving tacrolimus/sirolimus combination therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F05%3A00001129" target="_blank" >RIV/00023001:_____/05:00001129 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Lipid metabolism in renal transplant patients receiving tacrolimus/sirolimus combination therapy

Original language description

Introduction The administration of sirolimus has been reported to be associated with high serum cholesterol and high triglyceride values. In a large prospective, multicenter 6-month study in renal transplantation, basic parameters of lipid metabolism (total serum cholesterol and triglycerides) were systematically assessed in patients who received tacrolimus/mycophenolate mofetil/steroids (Tac/MMF), tacrolimus/0.5 mg sirolimus (SIR)/steroids (Tac/0.5SIR) on tacrolimus/2 mg sirolimus/steroids (Tac/2SIR).Methods For purposes of analysis, lipid parameters were classified using the National Kidney Foundation Dyslipidemia Classification definitions. Results Complete sets of data at all visits (baseline, months 1, 3, and 6) were available for 211 Tac/MMF, 210 Tac/0.5SIR, and 203 Tac/2SIR patients. Total serum cholesterol in the Tac/MMF group was 193.4 at baseline and 202.9 mg/dL at month 6. Values increased from 196 mg/dL to 212.5 mg/dL in Tac/0.5SIR and from 200 mg/dL to 230.5 mg/dL in Tac/

Czech name

Metabolismus lipidů u pacientů po transplantaci ledvin léčených kombinací takrolimus/sirolimus

Czech description

metabolismus lipidů, sirolimus, transplantace ledvin, cholesterol, triglyceridy

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FJ - Surgery including transplantology

OECD FORD branch

—

Project

—

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Transplantation Proceedings

ISSN

0041-1345

e-ISSN

—

Volume of the periodical

37

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

3

Pages from-to

1871-1873

UT code for WoS article

—

EID of the result in the Scopus database

—