Changes in the brain during long-term follow-up after liver transplantation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F12%3A00055831" target="_blank" >RIV/00023001:_____/12:00055831 - isvavai.cz</a>
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1002/jmri.23599/abstract;jsessionid=DE9D7588F719B27089FDD7B2D68285A9.d03t04" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/jmri.23599/abstract;jsessionid=DE9D7588F719B27089FDD7B2D68285A9.d03t04</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jmri.23599" target="_blank" >10.1002/jmri.23599</a>

Result language
angličtina
Original language name
Changes in the brain during long-term follow-up after liver transplantation
Original language description
PURPOSE: To examine changes in the brain before liver transplantation caused by the accumulation of paramagnetic ion deposits and to investigate recovery after liver transplantation over a long-term horizon. MATERIALS AND METHODS: Fifteen patients indicated for liver transplantation, 26 patients up to 2 years after, and 40 patients 8-15 years after liver transplantation were subjected to MR relaxometry. T(1) and T(2) relaxation times in the basal ganglia, thalamus, and white matter were evaluated. RESULTS: Relaxometry revealed a shortening of the relaxation times due to the deposition of paramagnetic ions in the basal ganglia before liver transplantation (P < 0.05), complete normalization of the relaxation times shortly after transplantation in the globus pallidus and caudate nucleus, and partial recovery of T(2) in the putamen. Relaxation times remained stable even 15 years posttransplantation. Increased relaxation times posttransplantation were found in the white matter and thalamus.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
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Project
<a href="/en/project/NS10523" target="_blank" >NS10523: Long-term evolution of morphology and metabolism in the brain after liver transplantation</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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