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The oxidized low-density lipoprotein/beta2-glycoprotein I complex is associated with abdominal obesity in healthy middle-aged men

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F13%3A00057605" target="_blank" >RIV/00023001:_____/13:00057605 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.karger.com/Article/FullText/343049" target="_blank" >http://www.karger.com/Article/FullText/343049</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1159/000343049" target="_blank" >10.1159/000343049</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The oxidized low-density lipoprotein/beta2-glycoprotein I complex is associated with abdominal obesity in healthy middle-aged men

  • Original language description

    Oxidized low-density lipoprotein (oxLDL) in complex with beta2-glycoprotein I (beta2GPI) has been associated with autoimmune diseases, diabetes mellitus, chronic renal disease and coronary atherosclerosis. The aim of our study was to determine whether plasma levels of oxLDL/beta2GPI complexes are associated with insulin resistance, inflammation and markers of endothelial damage in obese middle-aged men and, if so, whether oxLDL/beta2GPI correlates better with insulin resistance parameters than oxLDL, advanced oxidation protein products (AOPP) or thioredoxin. Methods: A total of 72 healthy men were recruited (41 obese and 31 nonobese individuals). Waist circumference >94 cm was used as the criterion for abdominal obesity. Results: The obese men demonstrated higher oxLDL/beta2GPI levels (p < 0.001), homeostasis model assessment of insulin resistance (p < 0.01) and intima-media thickness of the common carotid artery (p < 0.01). oxLDL/beta2GPI correlated with more insulin resistance parame

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Annals of nutrition and metabolism

  • ISSN

    0250-6807

  • e-ISSN

  • Volume of the periodical

    62

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    7

  • Pages from-to

    7-13

  • UT code for WoS article

    000314620900002

  • EID of the result in the Scopus database