Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F13%3A00058798" target="_blank" >RIV/00023001:_____/13:00058798 - isvavai.cz</a>

Alternative codes found

RIV/00064173:_____/13:N0000012

Result on the web

<a href="http://eurheartj.oxfordjournals.org/content/34/40/3117.long" target="_blank" >http://eurheartj.oxfordjournals.org/content/34/40/3117.long</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/eurheartj/eht342" target="_blank" >10.1093/eurheartj/eht342</a>

Result language

angličtina

Original language name

Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial

Original language description

AIM The objective of the Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT) was to determine whether aliskiren, a direct renin inhibitor, would improve post-discharge outcomes in patients with hospitalization for heart failure (HHF) with reducedejection fraction. This pre-specified subgroup analysis from the ASTRONAUT trial generates the hypothesis that the addition of aliskiren to standard HHF therapy in non-diabetic patients is generally well-tolerated and improves post-discharge outcomes and biomarker profiles. In contrast, diabetic patients receiving aliskiren appear to have worse post-discharge outcomes. Future prospective investigations are needed to confirm potential benefits of renin inhibition in a large cohort of HHF patients without DM.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European heart journal

ISSN

0195-668X

e-ISSN

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Volume of the periodical

34

Issue of the periodical within the volume

40

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

3117-3127

UT code for WoS article

000326292600011

EID of the result in the Scopus database

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