CD14+CD16+and CD14+CD163+monocyte subpopulations in kidney allograft transplantation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00058834" target="_blank" >RIV/00023001:_____/14:00058834 - isvavai.cz</a>

Result on the web

<a href="http://www.biomedcentral.com/1471-2172/15/4" target="_blank" >http://www.biomedcentral.com/1471-2172/15/4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/1471-2172-15-4" target="_blank" >10.1186/1471-2172-15-4</a>

Result language

angličtina

Original language name

CD14+CD16+and CD14+CD163+monocyte subpopulations in kidney allograft transplantation

Original language description

Monocytes represent a heterogeneuos population of cells subdivided according to the expression level of membrane antigens. A pro-inflammatory (intermediate/nonclassical) subpopulation of monocytes is defined by expression of CD16. CD163 seems to be characteristically preferentially expressed by immunosuppressive monocytes.The aim of our study was to avaluete the distribution of monocyte subpopulations in 71 patients with kidney allograft transplantation. The phenotype was evaluated by flow cytometry indefined time points. The proportions of peripheral CD14+CD16+ monocytes were downregulated immediately after the kidney transplantation and basiliximab treatment partially attenuated this trend. The transient downregulation of the CD14+CD16+ subpopulation was adjust to basal values in two months. The proportions of CD14+Cd163+ monocytes were transietlyupregulated early after the kidney transplantation and remained higher during the first month in most patients. In ATG treated patients, t

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EC - Immunology

OECD FORD branch

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Project

<a href="/en/project/GAP301%2F11%2F1568" target="_blank" >GAP301/11/1568: Cellular aspects of transplantation tolerance</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

BMC IMMUNOLOGY

ISSN

1471-2172

e-ISSN

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Volume of the periodical

15

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

1-10

UT code for WoS article

000332972400001

EID of the result in the Scopus database

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