Differential hemodynamic effects of exercise and volume expansion in people with and without heart failure

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F15%3A00059214" target="_blank" >RIV/00023001:_____/15:00059214 - isvavai.cz</a>
Result on the web
<a href="http://circheartfailure.ahajournals.org/content/8/1/41.full.pdf+html" target="_blank" >http://circheartfailure.ahajournals.org/content/8/1/41.full.pdf+html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001731" target="_blank" >10.1161/CIRCHEARTFAILURE.114.001731</a>

Result language
angličtina
Original language name
Differential hemodynamic effects of exercise and volume expansion in people with and without heart failure
Original language description
Background-Invasive hemodynamic exercise testing is commonly used in the evaluation of patients with suspected heart failure with preserved ejection fraction (HFpEF) or pulmonary hypertension. Saline loading has been suggested as an alternative provocative maneuver, but the hemodynamic changes induced by the 2 stresses have not been compared. Conclusions-Exercise elicits greater pulmonary capillary wedge pressure elevation compared with saline in HFpEF but not controls, suggesting that hemodynamic stresses beyond passive stiffness and increased venous return explain the development of pulmonary venous hypertension in HFpEF. Exercise testing is more sensitive than saline loading to detect hemodynamic derangements indicative of HFpEF.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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