Body composition changes in adult females after lifestyle intervention are influenced by the NYD-SP18 variant
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F15%3A00059699" target="_blank" >RIV/00023001:_____/15:00059699 - isvavai.cz</a>
Result on the web
<a href="http://apps.szu.cz/svi/cejph/show_en.php?kat=obsah/2015e-sup" target="_blank" >http://apps.szu.cz/svi/cejph/show_en.php?kat=obsah/2015e-sup</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Body composition changes in adult females after lifestyle intervention are influenced by the NYD-SP18 variant
Original language description
Aim: The study focuses on the analysis of the possible relationship between a common NYD-SP18 (rs6971091, G >A) gene polymorphism and weight loss after lifestyle intervention (combined dietary intake and physical activity) in overweight/obese females. Methods: We genotyped 139 unrelated non-diabetic Czech females (49.5 +/- 13.3 years, average BMI at baseline 32.2 +/- 4.6 kg/m(2)). Biochemical and anthropometrical measurements were performed before and after ten weeks of lifestyle intervention. Results: The mean weight loss achieved was 4.7 +/- 3.1 kg (p< 0.01). Carriers of the NYD-SP18 GG (N = 75) genotype lost significantly more body fat mass (p = 0.04) and gained more active muscle mass (p = 0.037) than the carriers of the A allele (N = 64). After adjustment of baseline values, both differences remained significant (p = 0.03 and p = 0.016). Conclusion: Overweight/obese female carriers of the NYD-SP18 rs6971091 GG genotype exhibited a more beneficial response to the intensive lifestyle intervention than others.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Central European Journal of Public Health
ISSN
1210-7778
e-ISSN
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Volume of the periodical
23
Issue of the periodical within the volume
Supplement S
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
4
Pages from-to
"S19"-"S22"
UT code for WoS article
000368324000004
EID of the result in the Scopus database
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