Nanomagnets for ultra-high field MRI: Magnetic properties and transverse relaxivity of silica-coated epsilon-Fe2O3
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F19%3A00077749" target="_blank" >RIV/00023001:_____/19:00077749 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22340/20:43919643
Result on the web
<a href="https://reader.elsevier.com/reader/sd/pii/S0304885319302355?token=D6AB1438B77D9405926D5A0B231F6E121B3DDAA8D57AB31EE9B0F27D2A7A647C7BFDB583499BEC6245909A69FD3FBFE9" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S0304885319302355?token=D6AB1438B77D9405926D5A0B231F6E121B3DDAA8D57AB31EE9B0F27D2A7A647C7BFDB583499BEC6245909A69FD3FBFE9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jmmm.2019.02.067" target="_blank" >10.1016/j.jmmm.2019.02.067</a>
Alternative languages
Result language
angličtina
Original language name
Nanomagnets for ultra-high field MRI: Magnetic properties and transverse relaxivity of silica-coated epsilon-Fe2O3
Original language description
Magnetic nanoparticles of iron oxides have received extensive attention in the biomedical research, e.g. as prospective contrast agents for T-2-weighted magnetic resonance imaging (MRI). The ability of a contrast agent to enhance the relaxation rate of H-1 nuclei in its vicinity is quantitatively described by its relaxivity. Among the polymorphs of the iron(III) oxide, the nanoparticulate epsilon-Fe2O3, distinguished by its high magnetocrystalline anisotropy resulting in a blocked state of single-domain particles up to the Curie temperature of similar to 500 K, has never been studied as a contrast agent for MRI before. We analyzed r(1) and r(2) relaxivities of epsilon-Fe(2)O(3 )nanoparticles coated with amorphous silica, particularly with the aim to determine their dependences on the external magnetic field, temperature, and thickness of the silica coating. The r(2) relaxivity was interpreted within the motional averaging and static dephasing regimes. MRI images at 11.75 T confirmed high applicability of epsilon-Fe2O3-based contrast agents in ultra-high fields. We present the first case study considering epsilon-Fe2O3 nanomagnets for prospective application in biomedicine, in particular for MRI in ultra-high fields. The study is complemented by a thorough investigation of magnetic properties of the nanoparticles, revealing some interesting anomalies.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
21001 - Nano-materials (production and properties)
Result continuities
Project
<a href="/en/project/GA16-04340S" target="_blank" >GA16-04340S: Oxide nanomagnets, their properties and interactions with biological systems</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of magnetism and magnetic materials
ISSN
0304-8853
e-ISSN
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Volume of the periodical
480
Issue of the periodical within the volume
June 15
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
10
Pages from-to
154-163
UT code for WoS article
000460508900021
EID of the result in the Scopus database
2-s2.0-85062147368