Nanomagnets for ultra-high field MRI: Magnetic properties and transverse relaxivity of silica-coated ε-Fe2O3

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F19%3A10391997" target="_blank" >RIV/00216208:11320/19:10391997 - isvavai.cz</a>

Alternative codes found

RIV/68378271:_____/19:00519491 RIV/00216208:11110/19:10391997

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=j0Ey6RuChD" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=j0Ey6RuChD</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jmmm.2019.02.067" target="_blank" >10.1016/j.jmmm.2019.02.067</a>

Result language

angličtina

Original language name

Nanomagnets for ultra-high field MRI: Magnetic properties and transverse relaxivity of silica-coated ε-Fe2O3

Original language description

Magnetic nanoparticles of iron oxides have received extensive attention in the biomedical research, e.g. as prospective contrast agents for T2-weighted magnetic resonance imaging (MRI). The ability of a contrast agent to enhance the relaxation rate of 1H nuclei in its vicinity is quantitatively described by its relaxivity. Among the polymorphs of the iron(III) oxide, the nanoparticulate ε-Fe2O3, distinguished by its high magnetocrystalline anisotropy resulting in a blocked state of single-domain particles up to the Curie temperature of ~500 K, has never been studied as a contrast agent for MRI before. We analyzed r1 and r2 relaxivities of ε-Fe2O3 nanoparticles coated with amorphous silica, particularly with the aim to determine their dependences on the external magnetic field, temperature, and thickness of the silica coating. The r2 relaxivity was interpreted within the motional averaging and static dephasing regimes. MRI images at 11.75 T confirmed high applicability of ε-Fe2O3-based contrast agents in ultra-high fields. We present the first case study considering ε-Fe2O3 nanomagnets for prospective application in biomedicine, in particular for MRI in ultra-high fields. The study is complemented by a thorough investigation of magnetic properties of the nanoparticles, revealing some interesting anomalies.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Magnetism and Magnetic Materials

ISSN

0304-8853

e-ISSN

—

Volume of the periodical

480

Issue of the periodical within the volume

February 2019

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

10

Pages from-to

154-163

UT code for WoS article

000460508900021

EID of the result in the Scopus database

2-s2.0-85062147368