Is the impact of conventional risk factors the same in men and women? Plea for a more gender-specific approach

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F19%3A00077920" target="_blank" >RIV/00023001:_____/19:00077920 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/19:10394369 RIV/00064203:_____/19:10394369 RIV/00064190:_____/19:N0000054 RIV/00216208:11110/19:10394369 RIV/00064165:_____/19:10394369

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0167527318370086?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0167527318370086?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijcard.2019.01.039" target="_blank" >10.1016/j.ijcard.2019.01.039</a>

Result language

angličtina

Original language name

Is the impact of conventional risk factors the same in men and women? Plea for a more gender-specific approach

Original language description

Cardiovascular disease (CVD) is the leading cause of death in women in developed countries. The traditional modifiable risk factors are able to explain the majority of CVD mortality. The aim of this review is to analyze gender-specific aspects of major conventional cardiovascular risk factors and to assess whether they have the same impact on CVD in women. Cigarette smoking remains the single largest preventable cause of cardiovascular morbidity and premature death worldwide. Women smoke less than men; however, smoking seems to be more harmful in women, particularly in oral contraceptive users. Obesity in the general population is more prevalent in women. Visceral adiposity is associated with insulin resistance and a higher risk of developing cardiovascular disease. Life expectancy in female diabetic patients is shorter than in men with diabetes; women with diabetes are also at higher risk of developing cardiovascular events. Changes of main lipid parameters in women are frequently associated with their hormonal status and/or hormonal treatment. Hypertension is highly prevalent in post-menopausal women and carries a higher risk of developing left ventricular hypertrophy, which, together with a greater increase in vascular and myocardial stiffness, results in a higher incidence of heart failure with preserved ejection fraction and a higher risk of developing stroke. The risk of abdominal aortic rupture is substantially higher in women. In conclusion, smoking, diabetes and hypertension seem to be more harmful in women. Therefore, the question is whether there should not be lower thresholds for initiating drug treatment in women with diabetes and hypertension. (C) 2019 Elsevier B.V. All rights reserved.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

<a href="/en/project/NV15-27109A" target="_blank" >NV15-27109A: Longitudinal trends in major cardiovascular risk factors and their predictive value in a population random sample, Czech post-MONICA study</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International journal of cardiology

ISSN

0167-5273

e-ISSN

—

Volume of the periodical

286

Issue of the periodical within the volume

July 1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

6

Pages from-to

214-219

UT code for WoS article

000465271500051

EID of the result in the Scopus database

2-s2.0-85060341215