Current vascular allograft procurement, cryopreservation and transplantation techniques in the Czech Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F19%3A00077974" target="_blank" >RIV/00023001:_____/19:00077974 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/19:00110189 RIV/00216208:11110/19:10394122 RIV/00216208:11150/19:10394122 RIV/00209775:_____/19:N0000024 and 5 more

Result on the web

<a href="http://www.advances.umed.wroc.pl/pdf/2019/28/4/529.pdf" target="_blank" >http://www.advances.umed.wroc.pl/pdf/2019/28/4/529.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17219/acem/90037" target="_blank" >10.17219/acem/90037</a>

Result language

angličtina

Original language name

Current vascular allograft procurement, cryopreservation and transplantation techniques in the Czech Republic

Original language description

Background. Vascular allotransplantations are performed worldwide in selected patients suffering from vascular prosthesis infection or critical limb ischemia. Either fresh or cryopreserved vascular allograft may be used. Objectives. In various points, we address several aspects (allograft procurement, cryopreservation and transplantation technique) of the program of vascular allotransplantations in the Czech Republic. Materials and methods. Vascular grafts retrieval has been done within multiorgan harvests using no-touch technique. Very short time of cold ischemia is achieved due to close cooperation with Tissue Establishment where the following processing of cryopreservation is performed. Meeting all necessary quality criteria is a prerequisity for releasing grafts for clinical application. Standardized thawing protocol and surgical handling aims to minimize microfractures before implantation. Results. Based on experimental and clinical work, the first validation of cryopreserved arterial and venous grafts for clinical use was performed between 2011 and 2013 in the Czech Republic. The developement of storage of vascular tissue in banks was stimulated in 2000-2010 by the issue of EU directives and national harmonized norms, aimed at assurance of high quality and safety of cells and tissues used for transplantations in humans. Conclusions. There are several crucial moments affecting final quality, including graft retrieval within a multiorgan harvest, short ischemic time, cryopreservation, and thawing technique used. The recommended surgical handling during implantation may also affect results and graft-related complications.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30213 - Transplantation

Project

—

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Advances in clinical and experimental medicine

ISSN

1899-5276

e-ISSN

—

Volume of the periodical

28

Issue of the periodical within the volume

4

Country of publishing house

PL - POLAND

Number of pages

6

Pages from-to

529-534

UT code for WoS article

000466338100012

EID of the result in the Scopus database

2-s2.0-85065518953