Anti-inflammatory effect of fish oil in human adipose tissue

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F21%3A00081547" target="_blank" >RIV/00023001:_____/21:00081547 - isvavai.cz</a>
Result on the web
<a href="https://www.nature.com/articles/s41366-021-00889-0" target="_blank" >https://www.nature.com/articles/s41366-021-00889-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41366-021-00889-0" target="_blank" >10.1038/s41366-021-00889-0</a>

Result language
angličtina
Original language name
Anti-inflammatory effect of fish oil in human adipose tissue
Original language description
Proportions of palmitic and palmiooleic acids correlated positively with that of proinflammatory macrophages, whereas a negative correlation with alfa-linolenic and eicosopentaenic acids was found, and the same association was observed for the n3 PUFA to n3/n6 ratio. The proportion of pro-inflammatory macrophages reflected the current diet of living kidney donors (LKD) subjects. The dietary score (increasing with low vegetable fat proportion and low omega3 fatty acid consumption) correlated positively with the proportion of pro-inflammatory macrophages in visceral adipose tissue. Based on our results, it seems plasible that anti-inflammatory effect of fish oil is mediated by changes in adipose tissue macrophage polarization.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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