Functional properties of Dunaliella salina and its positive effect on probiotics
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F22%3A00083552" target="_blank" >RIV/00023001:_____/22:00083552 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22330/22:43924679 RIV/60461373:22340/22:43924679 RIV/26722861:_____/22:N0000062 RIV/00216208:11110/22:10453376 RIV/60460709:41210/22:92022
Result on the web
<a href="https://www.mdpi.com/1660-3397/20/12/781" target="_blank" >https://www.mdpi.com/1660-3397/20/12/781</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/md20120781" target="_blank" >10.3390/md20120781</a>
Alternative languages
Result language
angličtina
Original language name
Functional properties of Dunaliella salina and its positive effect on probiotics
Original language description
The unicellular green microalga Dunaliella is a potential source of a wide range of nutritionally important compounds applicable to the food industry. The aim of this study was to assess the effect of Dunaliella salina dried biomass on the growth and adherence of 10 strains of Lactobacillus, Lacticaseibacillus, and Bifidobacterium. The immunomodulatory, antioxidant, and cytotoxic effects of D. salina on human peripheral mononuclear cells and simulated intestinal epithelial cell lines Caco-2 and HT-29 were evaluated. Furthermore, the hypocholesterolemic effects of the microalgae on lipid metabolism in rats fed a high-fat diet were analyzed. The addition of D. salina biomass had a positive effect on the growth of nine out of 10 probiotics and promoted the adherence of three bifidobacteria strains to human cell lines. The antioxidant and immunomodulatory properties of D. salina were concentration-dependent. The inflammatory cytokines (TNF-alpha and IL-6) were significantly increased following Dunaliella stimulation at the lowest concentration (0.5% w/v). Eight week supplementation of D. salina to the diet of hypercholesteromic rats significantly decreased the serum concentrations of LDL-C, VLDL, IDL-B, and IDL-C. D. salina is not cytotoxic in intestinal cell models; it promotes adherence of selected bifidobacteria, it affords immunomodulatory and antioxidant effects, and its addition to diets may help decrease atherosclerosis risk factors.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Marine drugs
ISSN
1660-3397
e-ISSN
1660-3397
Volume of the periodical
20
Issue of the periodical within the volume
12
Country of publishing house
CH - SWITZERLAND
Number of pages
13
Pages from-to
"art. no. 781"
UT code for WoS article
000902635000001
EID of the result in the Scopus database
2-s2.0-85144504181