Different effects of cyclical ketogenic vs. nutritionally balanced reduction diet on serum concentrations of myokines in healthy young males undergoing combined resistance/aerobic training
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F23%3A00083874" target="_blank" >RIV/00023001:_____/23:00083874 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/23:10458609 RIV/60461373:22330/23:43925951 RIV/00064165:_____/23:10458609
Result on the web
<a href="https://www.mdpi.com/2072-6643/15/7/1720" target="_blank" >https://www.mdpi.com/2072-6643/15/7/1720</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/nu15071720" target="_blank" >10.3390/nu15071720</a>
Alternative languages
Result language
angličtina
Original language name
Different effects of cyclical ketogenic vs. nutritionally balanced reduction diet on serum concentrations of myokines in healthy young males undergoing combined resistance/aerobic training
Original language description
Myokines represent important regulators of muscle metabolism. Our study aimed to explore the effects of a cyclical ketogenic reduction diet (CKD) vs. a nutritionally balanced reduction diet (RD) combined with regular resistance/aerobic training in healthy young males on serum concentrations of myokines and their potential role in changes in physical fitness. Twenty-five subjects undergoing regular resistance/aerobic training were randomized to the CKD (n = 13) or RD (n = 12) groups. Anthropometric and spiroergometric parameters, muscle strength, biochemical parameters, and serum concentrations of myokines and cytokines were assessed at baseline and after 8 weeks of intervention. Both diets reduced body weight, body fat, and BMI. Muscle strength and endurance performance were improved only by RD. Increased musclin (32.9 pg/mL vs. 74.5 pg/mL, p = 0.028) and decreased osteonectin levels (562 pg/mL vs. 511 pg/mL, p = 0.023) were observed in RD but not in the CKD group. In contrast, decreased levels of FGF21 (181 pg/mL vs. 86.4 pg/mL, p = 0.003) were found in the CKD group only. Other tested myokines and cytokines were not significantly affected by the intervention. Our data suggest that changes in systemic osteonectin and musclin levels could contribute to improved muscle strength and endurance performance and partially explain the differential effects of CKD and RD on physical fitness.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
<a href="/en/project/LX22NPO5104" target="_blank" >LX22NPO5104: National Institute for Research of Metabolic and Cardiovascular Diseases</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nutrients
ISSN
2072-6643
e-ISSN
2072-6643
Volume of the periodical
15
Issue of the periodical within the volume
7
Country of publishing house
CH - SWITZERLAND
Number of pages
12
Pages from-to
"art. no. 1720"
UT code for WoS article
000970158500001
EID of the result in the Scopus database
2-s2.0-85152336148