Small artery disease as a predictor of wound healing in patients with diabetic foot after revascularization
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F25%3A00085696" target="_blank" >RIV/00023001:_____/25:00085696 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/25:10496057
Result on the web
<a href="https://journals.sagepub.com/doi/10.1177/15347346251323938" target="_blank" >https://journals.sagepub.com/doi/10.1177/15347346251323938</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/15347346251323938" target="_blank" >10.1177/15347346251323938</a>
Alternative languages
Result language
angličtina
Original language name
Small artery disease as a predictor of wound healing in patients with diabetic foot after revascularization
Original language description
The aim of study was to confirm the hypothesis that advanced medial arterial calcification (MAC)/ small artery disease (SAD), much like the progression of peripheral arterial disease (PAD) stages can adversely impact the outcomes in DFU patients, even after successful endovascular procedures. In retrospective study, we enrolled 54 patients with DFUs who underwent percutaneous transluminal angioplasty (PTA). MAC was quantified using a three-level scoring system based on radiographs. Patients were categorized based on their MAC score into three groups. Study groups were compared in terms of primary DFU outcomes (healing, amputations) and secondary DFU outcomes (mortality, changes in transcutaneous oxygen pressure (TcPO2)) three and six months after PTA. The MAC/SAD score increased significantly with age (p = 0.014). The MAC/SAD score was't associated with the risk of amputation or the healing of DFUs up to three months after revascularization. However, a significant association was observed after six months (p = 0.043). The MAC/SAD score correlated significantly with severity of PAD, as classified by the Global Limb Anatomic Staging System (p = 0.042) and the Graziani system (p = 0.019). We found a negative correlation between the MAC/SAD score and absolute levels of TcPO2 after PTA. MAC/SAD score was significantly associated with long-term unhealed DFUs and the risk of lower limb amputations.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International journal of lower extremity wounds
ISSN
1534-7346
e-ISSN
1552-6941
Volume of the periodical
24
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
621-629
UT code for WoS article
001444482500001
EID of the result in the Scopus database
2-s2.0-105000113998