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Ten millennia of hepatitis B virus evolution

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023272%3A_____%2F21%3A10135236" target="_blank" >RIV/00023272:_____/21:10135236 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.science.org/doi/abs/10.1126/science.abi5658" target="_blank" >https://www.science.org/doi/abs/10.1126/science.abi5658</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1126/science.abi5658" target="_blank" >10.1126/science.abi5658</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Ten millennia of hepatitis B virus evolution

  • Original language description

    Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd millennium BCE. The only remnant of this prehistoric HBV diversity is the rare genotype G, which appears to have reemerged during the HIV pandemic.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10607 - Virology

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Science

  • ISSN

    1095-9203

  • e-ISSN

  • Volume of the periodical

    374

  • Issue of the periodical within the volume

    6564

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    182-188

  • UT code for WoS article

    000704920400041

  • EID of the result in the Scopus database

    2-s2.0-85118031627