Earliest modern human genomes constrain timing of Neandertal admixture

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023272%3A_____%2F24%3A10136717" target="_blank" >RIV/00023272:_____/24:10136717 - isvavai.cz</a>
Result on the web
<a href="https://www.nature.com/articles/s41586-024-08420-x" target="_blank" >https://www.nature.com/articles/s41586-024-08420-x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41586-024-08420-x" target="_blank" >10.1038/s41586-024-08420-x</a>

Result language
angličtina
Original language name
Earliest modern human genomes constrain timing of Neandertal admixture
Original language description
Modern humans arrived in Europe more than 45,000 years ago, overlapping at least 5,000 years with Neanderthals1-4. Limited genomic data from these early modern humans have shown that at least two genetically distinct groups inhabited Europe, represented by Zlaty kun, Czechia3 and Bacho Kiro, Bulgaria2. Here we deepen our understanding of early modern humans by analyzing one high-coverage genome and five low-coverage genomes from ~45,000 year-old remains from Ilsenhohle in Ranis, Germany4, and a further high-coverage genome from Zlaty kun. We show that distant familial relationships link the Ranis and Zlaty kun individuals and that they were part of the same small, isolated population that represents the deepest known split from the Out-of-Africa lineage. Ranis genomes harbor Neanderthal segments that originate from a single admixture event shared with all non-Africans that we date to ~45,000-49,000 years ago. This implies that ancestors of all non-Africans sequenced to-date resided in a common population at this time, and further suggests that modern human remains older than 50,000 years from outside Africa represent different non-African populations.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10620 - Other biological topics

Project
<a href="/en/project/GA23-06822S" target="_blank" >GA23-06822S: Human skeletal remains from Zlaty kůň: The re-examination and new interpretations of the 20th century excavations at Koněprusy Caves</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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