Clinical Features of Myositis: Muscular Manifestation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023728%3A_____%2F20%3AN0000012" target="_blank" >RIV/00023728:_____/20:N0000012 - isvavai.cz</a>
Result on the web
<a href="https://link-springer-com.ezproxy.is.cuni.cz/chapter/10.1007/978-3-030-15820-0_5" target="_blank" >https://link-springer-com.ezproxy.is.cuni.cz/chapter/10.1007/978-3-030-15820-0_5</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Clinical Features of Myositis: Muscular Manifestation
Original language description
The main muscular symptom of inflammatory myopathies is muscle weakness. It is mostly symmetrical and proximally located in patients with polymyositis (PM), dermatomyositis (DM), and immune mediated necrotising myopathy (IMNM). In IBM it is usually asymmetric and more often distal. In amyopathic DM weakness may not be present or clinically obvious and sometimes can only be found when tested for. Muscle pain may be present, but not as a main symptom, and if predominant, it should raise suspicion for other diagnosis. Muscular weakness is usually caused by disease activity, but also acquired muscle damage or drug-induced myopathy could be the reason. Dysphagia is a frequent symptom and is due to active inflammation of upper esophagus muscles. Treatment-resistant dysphagia may be the consequence of muscle fibrosis. MRI is a useful technique to visualize inflammation, which manifests as edema on MR images. Atrophy, fibrosis, and fatty infiltration can also be observed. A number of conditions may mimic inflammatory myopathy. The presence of ocular or facial muscle involvement, scapular winging, second-wind phenomenon, prominent distal weakness, exercise-induced cramps, fasting-associated symptoms, fasciculations, myotonia, and dominant pain but also nonresponse to treatment, absence of myositis autoantibodies, lack of any extramuscular symptoms, and possibly also history of the use of myopathic drugs should lead to suspicion of neuropathy, muscle dystrophy, metabolic myopathy, endocrinopathy, toxic myopathy, or fibromyalgia.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30226 - Rheumatology
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Managing Myositis: A Practical Guide
ISBN
978-3-030-15819-4
Number of pages of the result
10
Pages from-to
37-46
Number of pages of the book
364
Publisher name
Springer
Place of publication
Cham
UT code for WoS chapter
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