Antiplatelet therapy versus observation in low-risk essential thrombocythemia with a CALR mutation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F16%3A00011556" target="_blank" >RIV/00023736:_____/16:00011556 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3324/haematol.2016.146654" target="_blank" >http://dx.doi.org/10.3324/haematol.2016.146654</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3324/haematol.2016.146654" target="_blank" >10.3324/haematol.2016.146654</a>
Alternative languages
Result language
angličtina
Original language name
Antiplatelet therapy versus observation in low-risk essential thrombocythemia with a CALR mutation
Original language description
The role of antiplatelet therapy as primary prophylaxis of thrombosis in low-risk essential thrombocythemia has not been studied in randomized clinical trials. We assessed the benefit/risk of low-dose aspirin in 433 patients with low-risk essential thrombocythemia (271 with a CALR mutation, 162 with a JAK2(V617F) mutation) who were on antiplatelet therapy or observation only. In conclusion, in patients with low-risk, CALR-mutated essential thrombocythemia, low-dose aspirin does not reduce the risk of thrombosis and may increase the risk of bleeding.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Haematologica/The hematology journal
ISSN
0390-6078
e-ISSN
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Volume of the periodical
101
Issue of the periodical within the volume
8
Country of publishing house
IT - ITALY
Number of pages
6
Pages from-to
926-931
UT code for WoS article
000381941900015
EID of the result in the Scopus database
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