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Adhesion structures in leukemia cells and their regulation by Src family kinases

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F18%3A00011770" target="_blank" >RIV/00023736:_____/18:00011770 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.1080/19336918.2017.1344796" target="_blank" >https://doi.org/10.1080/19336918.2017.1344796</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/19336918.2017.1344796" target="_blank" >10.1080/19336918.2017.1344796</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Adhesion structures in leukemia cells and their regulation by Src family kinases

  • Original language description

    Interaction of leukemia blasts with the bone marrow extracellular matrix often results in protection of leukemia cells from chemotherapy and in persistence of the residual disease which is on the basis of subsequent relapses. The adhesion signaling pathways have been extensively studied in adherent cells as well as in mature hematopoietic cells, but the adhesion structures and signaling in hematopoietic stem and progenitor cells, either normal or malignant, are much less explored. We analyzed the interaction of leukemia cells with fibronectin (FN) using interference reflection microscopy, immunofluorescence, measurement of adherent cell fraction, real-time microimpedance measurement and live cell imaging.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30205 - Hematology

Result continuities

  • Project

    <a href="/en/project/GA16-16169S" target="_blank" >GA16-16169S: Analysis of the role of PAK family kinases in the regulation of hematopoietic cell interaction with extracellular matrix proteins</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cell adhesion & migration

  • ISSN

    1933-6918

  • e-ISSN

  • Volume of the periodical

    12

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    13

  • Pages from-to

    286-298

  • UT code for WoS article

    000452035500010

  • EID of the result in the Scopus database

    2-s2.0-85027845598