Adhesion structures in leukemia cells and their regulation by Src family kinases
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F18%3A00011770" target="_blank" >RIV/00023736:_____/18:00011770 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1080/19336918.2017.1344796" target="_blank" >https://doi.org/10.1080/19336918.2017.1344796</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/19336918.2017.1344796" target="_blank" >10.1080/19336918.2017.1344796</a>
Alternative languages
Result language
angličtina
Original language name
Adhesion structures in leukemia cells and their regulation by Src family kinases
Original language description
Interaction of leukemia blasts with the bone marrow extracellular matrix often results in protection of leukemia cells from chemotherapy and in persistence of the residual disease which is on the basis of subsequent relapses. The adhesion signaling pathways have been extensively studied in adherent cells as well as in mature hematopoietic cells, but the adhesion structures and signaling in hematopoietic stem and progenitor cells, either normal or malignant, are much less explored. We analyzed the interaction of leukemia cells with fibronectin (FN) using interference reflection microscopy, immunofluorescence, measurement of adherent cell fraction, real-time microimpedance measurement and live cell imaging.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
<a href="/en/project/GA16-16169S" target="_blank" >GA16-16169S: Analysis of the role of PAK family kinases in the regulation of hematopoietic cell interaction with extracellular matrix proteins</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cell adhesion & migration
ISSN
1933-6918
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
286-298
UT code for WoS article
000452035500010
EID of the result in the Scopus database
2-s2.0-85027845598