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Targeting the cleavage factor and polyadenylation signal of pre-mRNA as methods for silencing the causative gene of the disease

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F19%3A00012656" target="_blank" >RIV/00023736:_____/19:00012656 - isvavai.cz</a>

  • Result on the web

    <a href="https://novapublishers.com/shop/a-closer-look-at-polyadenylation/" target="_blank" >https://novapublishers.com/shop/a-closer-look-at-polyadenylation/</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Targeting the cleavage factor and polyadenylation signal of pre-mRNA as methods for silencing the causative gene of the disease

  • Original language description

    The majority of eukaryotic mRNAs are polyadenylated at their 3´end. This poly(A) tail is not encoded by DNA and is added cotranscriptionally. Cleavage and polyadenylation specific factor (CPSF1) is part of multiple subunit factors required for a site-specific cleavage, which is involved in determining specificity and efficiency of the 3´end processing of pre-mRNAs in the nucleus by recognizing teh polyadenylation signal

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    30205 - Hematology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    A closer look at polyadenylation

  • ISBN

    978-1-53615-355-2

  • Number of pages of the result

    20

  • Pages from-to

    1-20

  • Number of pages of the book

    213

  • Publisher name

    Nova publishers

  • Place of publication

    New York

  • UT code for WoS chapter