Nucleophosmin in leukemia: consequences of anchor loss

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F19%3A00012664" target="_blank" >RIV/00023736:_____/19:00012664 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1016/j.biocel.2019.04.007" target="_blank" >https://doi.org/10.1016/j.biocel.2019.04.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.biocel.2019.04.007" target="_blank" >10.1016/j.biocel.2019.04.007</a>

Result language

angličtina

Original language name

Nucleophosmin in leukemia: consequences of anchor loss

Original language description

Nucleophosmin (NPM), one of the most abundant nucleolar proteins, has crucial functions in ribosome biogenesis, cell cycle control, and DNA-damage repair. In human cells, NPM occurs mainly in oligomers. It functions as a chaperone, undergoes numerous interactions and forms part of many protein complexes. Although NPM role in carcinogenesis is not fully elucidated, a variety of tumor suppressor as well as oncogenic activities were described. NPM is overexpressed, fused with other proteins, or mutated in various tumor types.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30205 - Hematology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International journal of biochemistry and cell biology

ISSN

1357-2725

e-ISSN

—

Volume of the periodical

111

Issue of the periodical within the volume

[June]

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

52-62

UT code for WoS article

000470192000008

EID of the result in the Scopus database

2-s2.0-85064622523