Identifying risk factors and optimizing standard of care for patients with acquired haemophilia A: results from a Czech patient cohort
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F20%3A00013037" target="_blank" >RIV/00023736:_____/20:00013037 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/20:10414179
Result on the web
<a href="https://doi.org/10.1111/hae.14084" target="_blank" >https://doi.org/10.1111/hae.14084</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/hae.14084" target="_blank" >10.1111/hae.14084</a>
Alternative languages
Result language
angličtina
Original language name
Identifying risk factors and optimizing standard of care for patients with acquired haemophilia A: results from a Czech patient cohort
Original language description
Acquired haemophilia A (AHA) is a rare autoimmune disorder, characterized by bleeds of varying severity caused by autoantibodies against factor VIII (FVIII). Identify risk factors associated with AHA-related deaths/relapses and assess the effect of increased corticosteroid doses. AHA patients treated across two specialist centres in the Czech Republic, generally receiving first-line haemostatic therapy with rFVIIa and immunosuppression with corticosteroids/cyclophosphamide, were included. We analysed the association between early death (within 8 weeks of diagnosis [considered disease-related]) and age, malignancy, FVIII levels and bleeding severity. Risk factors associated with reduced 2-year survival and relapse incidence, and the effect of increased corticosteroid doses on early death and remission were also assessed.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Haemophilia
ISSN
1351-8216
e-ISSN
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Volume of the periodical
26
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
643-651
UT code for WoS article
000543243500001
EID of the result in the Scopus database
2-s2.0-85087172640