How immune-cell fate and function are determined by metabolic pathway choice: the bioenergetics underlying the immune response
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F21%3A00013145" target="_blank" >RIV/00023736:_____/21:00013145 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/21:00075245 RIV/00216224:14110/21:00120840
Result on the web
<a href="https://doi.org/10.1002/bies.202000067" target="_blank" >https://doi.org/10.1002/bies.202000067</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/bies.202000067" target="_blank" >10.1002/bies.202000067</a>
Alternative languages
Result language
angličtina
Original language name
How immune-cell fate and function are determined by metabolic pathway choice: the bioenergetics underlying the immune response
Original language description
Immune cells are highly dynamic in their response to the tissue environment. Most immune cells rapidly change their metabolic profile to obtain sufficient energy to engage in defensive or homeostatic processes. Here, we discuss how different immune-cell types gain a sufficient energy supply. We then explain how immune cells perform various functions under challenged conditions and expend energy to sustain homeostasis Finally, we speculate on how the immune-cell metabolic profile might be modulated in health and disease, by manipulating nutrient availability. By such intervention, the recovery of patient with dysregulated immune system responses might be sped up and the fitness of an individual efficiently restored.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BioEssays
ISSN
0265-9247
e-ISSN
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Volume of the periodical
43
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
15
Pages from-to
"art. no. 2000067"
UT code for WoS article
000589588300001
EID of the result in the Scopus database
2-s2.0-85097162588