Phenotype and oxidative burst of low-density neutrophil subpopulations are altered in common variable immunodeficiency patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F24%3A00013584" target="_blank" >RIV/00023736:_____/24:00013584 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1002/cyto.b.22150" target="_blank" >https://doi.org/10.1002/cyto.b.22150</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/cyto.b.22150" target="_blank" >10.1002/cyto.b.22150</a>
Alternative languages
Result language
angličtina
Original language name
Phenotype and oxidative burst of low-density neutrophil subpopulations are altered in common variable immunodeficiency patients
Original language description
Common variable immunodeficiency disorder (CVID) is the most common form of primary antibody immunodeficiency. Due to low antibody levels, CVID patients receive intravenous or subcutaneous immunoglobulin replacement therapy as treatment. CVID is associated with the chronic activation of granulocytes, including an increased percentage of low-density neutrophils (LDNs). In this study, we examined changes in the percentage of LDNs and the expression of their surface markers in 25 patients with CVID and 27 healthy donors (HD) after in vitro stimulation of whole blood using IVIg. An oxidative burst assay was used to assess the functionality of LDNs.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cytometry part B: clinical cytometry
ISSN
0196-4763
e-ISSN
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Volume of the periodical
106
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
14
Pages from-to
99-112
UT code for WoS article
001109148500001
EID of the result in the Scopus database
2-s2.0-85177603270