Findings from bipolar offspring studies: methodology matters

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F11%3A00001215" target="_blank" >RIV/00023752:_____/11:00001215 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1111/j.1751-7893.2011.00276.x" target="_blank" >http://dx.doi.org/10.1111/j.1751-7893.2011.00276.x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1751-7893.2011.00276.x" target="_blank" >10.1111/j.1751-7893.2011.00276.x</a>

Result language
angličtina
Original language name
Findings from bipolar offspring studies: methodology matters
Original language description
Abstract: Aim: High-risk studies provide the opportunity to describe the early natural history of bipolar disorder (BD); however, findings have varied substantially. In this review, we compare different methods of ascertainment and assessment, and theirimpact on study findings. Methods: Through a literature search, we identified 11 high-risk studies meeting inclusion criteria for this review. Studies included were those that focused on lifetime psychopathology in the offspring as the main outcome and provided adequate information on the methods of family ascertainment, as well as on parent and offspring assessment. We compared and contrasted psychopathological outcomes in the offspring among the studies using different methods. Results: High-risk studies that identified affected parents through their involvement in neurobiological research and confirmed diagnosis in the parent and offspring through best estimate procedures tended to report lower rates of co-morbidity in the proband pa
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
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Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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