Two immunoassays for the detection of 2C-B and related hallucinogenic phenethylamines
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F19%3A43920082" target="_blank" >RIV/00023752:_____/19:43920082 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22330/19:43918508 RIV/60461373:22810/19:43918508
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S1056871918307330?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1056871918307330?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.vascn.2018.11.001" target="_blank" >10.1016/j.vascn.2018.11.001</a>
Alternative languages
Result language
angličtina
Original language name
Two immunoassays for the detection of 2C-B and related hallucinogenic phenethylamines
Original language description
Decellularized human pericardium is under study as an allogenic material for cardiovascular applications. The effects of crosslinking on the mechanical properties of decellularized pericardium were determined with a uniaxial tensile test, and the effects of crosslinking on the collagen structure of decellularized pericardium were determined by multiphoton microscopy. The viability of human umbilical vein endothelial cells seeded on decellularized human pericardium and on pericardium strongly and weakly crosslinked with glutaraldehyde and with genipin was evaluated by means of an MTSassay. The viability of the cells, measured by their metabolic activity, decreased considerably when the pericardium was crosslinked with glutaraldehyde. Conversely, the cell viability increased when the pericardium was crosslinked with genipin. Coating both non-modified pericardium and crosslinked pericardium with a fibrin mesh or with a mesh containing attached heparin and/or fibronectin led to a significant increase in cell viability. The highest degree of viability was attained for samples that were weakly crosslinked with genipin and modified by means of a fibrin and fibronectin coating. The results indicate a method by which in vivo endothelialization of human cardiac allografts or xenografts could potentially be encouraged.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30108 - Toxicology
Result continuities
Project
<a href="/en/project/VI20172020056" target="_blank" >VI20172020056: New synthetics drugs - complex interdisciplinary research centre</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Pharmacological and Toxicological Methods
ISSN
1056-8719
e-ISSN
—
Volume of the periodical
95
Issue of the periodical within the volume
January–February
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
36-46
UT code for WoS article
000454124000006
EID of the result in the Scopus database
2-s2.0-85057317097