Evolutionary origins of chemical synapses
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F20%3A43920245" target="_blank" >RIV/00023752:_____/20:43920245 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0083672920300339?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0083672920300339?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/bs.vh.2020.04.009" target="_blank" >10.1016/bs.vh.2020.04.009</a>
Alternative languages
Result language
angličtina
Original language name
Evolutionary origins of chemical synapses
Original language description
Synaptic transmission is a fundamental neurobiological process by which neurons interact with each other and non-neuronal cells. The process enables release of active substances from the presynaptic neuron onto receptive elements of postsynaptic cells, inducing waves of spreading excitation. While much has been learned about the cellular and molecular mechanisms enabling and governing transmitter release and sensing, the evolutionary origin of synaptic connections remains obscure. Herein, we review emerging evidence and concepts suggesting that key components of chemical synapses arose independently, in different functional and biological contexts, before the rise of neurons and multicellular living forms. We argue that throughout evolution, distinct synaptic constituents have been co-opted from ancestral forms for a new role in early metazoans, leading to the rise of current chemical synapses and neurotransmission. Such an eclectic model of the origin of chemical synapses agrees with and supports the pluralistic hypothesis of evolutionary change.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
50103 - Cognitive sciences
Result continuities
Project
<a href="/en/project/LO1611" target="_blank" >LO1611: Sustainability for The National Institute of Mental Health</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Vitamins and Hormones
ISSN
0083-6729
e-ISSN
—
Volume of the periodical
114
Issue of the periodical within the volume
2020
Country of publishing house
US - UNITED STATES
Number of pages
21
Pages from-to
1-21
UT code for WoS article
000612641100002
EID of the result in the Scopus database
2-s2.0-85087395425