Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F22%3A43920869" target="_blank" >RIV/00023752:_____/22:43920869 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/22:43923000
Result on the web
<a href="https://link.springer.com/article/10.1007/s00406-021-01366-5" target="_blank" >https://link.springer.com/article/10.1007/s00406-021-01366-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00406-021-01366-5" target="_blank" >10.1007/s00406-021-01366-5</a>
Alternative languages
Result language
angličtina
Original language name
Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses
Original language description
Personality traits influence risk for suicidal behavior. We examined phenotype- and genotype-level associations between the Big Five personality traits and suicidal ideation and attempt in major depressive, bipolar and schizoaffective disorder, and schizophrenia patients (N = 3012) using fixed- and random-effects inverse variance-weighted meta-analyses. Suicidal ideations were more likely to be reported by patients with higher neuroticism and lower extraversion phenotypic scores, but showed no significant association with polygenic load for these personality traits. Our findings provide new insights into the association between personality and suicidal behavior across mental illnesses and suggest that the genetic component of personality traits is unlikely to have strong causal effects on suicidal behavior.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Archives of Psychiatry and Clinical Neuroscience
ISSN
0940-1334
e-ISSN
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Volume of the periodical
272
Issue of the periodical within the volume
8
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
1611-1620
UT code for WoS article
000753708400001
EID of the result in the Scopus database
2-s2.0-85126130537