Revisiting monoamine oxidase inhibitors: A potential dual-action therapy for patients with prostate cancer and comorbid depression?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F23%3A43921109" target="_blank" >RIV/00023752:_____/23:43921109 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/23:10465025 RIV/00216208:11120/23:43925763
Result on the web
<a href="https://journals.sagepub.com/doi/10.1177/02698811231179808" target="_blank" >https://journals.sagepub.com/doi/10.1177/02698811231179808</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/02698811231179808" target="_blank" >10.1177/02698811231179808</a>
Alternative languages
Result language
angličtina
Original language name
Revisiting monoamine oxidase inhibitors: A potential dual-action therapy for patients with prostate cancer and comorbid depression?
Original language description
This article reviews the potential dual role of monoamine oxidase inhibitors (MAOIs) in the treatment of castration-resistant prostate cancer (CRPC) and the comorbid depression often seen in patients with CRPC. It examines the complex interactions between various cellular and neuroendocrine pathways, with particular emphasis on the intertwined roles of the hypothalamic-pituitary-adrenal (HPA) axis, androgenic hormones and their receptors in the development of both disorders. The text also emphasises the need for rigorous research to understand the complex relationship between MAOIs, CRPC and comorbid depression, and to investigate common biomarkers of the two conditions. Such findings may shed light on the potential therapeutic efficacy of MAOIs in the treatment of CRPC patients with comorbid depression.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30217 - Urology and nephrology
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Psychopharmacology
ISSN
0269-8811
e-ISSN
1461-7285
Volume of the periodical
37
Issue of the periodical within the volume
11
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
1157-1160
UT code for WoS article
001009976100001
EID of the result in the Scopus database
2-s2.0-85162711116