Unveiling stimulus transduction artifacts in auditory steady-state response experiments: Characterization, risks, and mitigation strategies

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F25%3A43921457" target="_blank" >RIV/00023752:_____/25:43921457 - isvavai.cz</a>

Alternative codes found

RIV/68407700:21460/25:00379312 RIV/00216208:11120/25:43927782

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S1746809424011868?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1746809424011868?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.bspc.2024.107128" target="_blank" >10.1016/j.bspc.2024.107128</a>

Result language

angličtina

Original language name

Unveiling stimulus transduction artifacts in auditory steady-state response experiments: Characterization, risks, and mitigation strategies

Original language description

This scientific paper addresses the potential risk of spurious responses in neuroscientific auditory steady-state response (ASSR) experiments attributed to transduction artifacts. The focus is particularly on click train stimuli, given their spectral content in the frequency range of interest (e.g., 40 Hz). Building upon a pilot experiment demonstrating the existence of the artifact in a phantom head, this study focuses on the characterization of stimulus artifacts in extended measurements with phantoms and the evaluation of associated risks in experiments involving human subjects, where 15 subjects were stimulated by headphones and speakers, which served as a control condition. The investigation is divided into two parts: the first part scrutinizes stimulus artifact properties crucial for mitigation, while the second part assesses risks in ASSR experiments with human subjects based on the characterized artifact. The discussion covers stimulus characterization, experimental setups with phantoms, and experiments with human subjects, exploring potential sources of the artifact, its spatial properties, and the influence of re-referencing, which can suppress a less prominent artifact while significantly increasing the prominent and focused artifact. The results reveal the role of headphone cables as a source of stimulus artifacts, along with the surprising impact of headphone transducers. The study emphasizes the need for careful experimental design. We proposes specific data analyses assessing cross- frequency correlation maps and the topographic structure of the brain response at higher harmonic frequencies of the fundamental 40 Hz component. These steps, if applied appropriately, will prevent misinterpretation of stimulus artifacts as genuine brain responses in ASSR experiments.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20601 - Medical engineering

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Signal Processing and Control

ISSN

1746-8094

e-ISSN

1746-8108

Volume of the periodical

101

Issue of the periodical within the volume

"Article Number 107128"

Country of publishing house

GB - UNITED KINGDOM

Number of pages

14

Pages from-to

1-14

UT code for WoS article

001396199500001

EID of the result in the Scopus database

2-s2.0-85210130199