Synthesis of (19-2H3)-analogs of dehydroepiandrosterone and pregnanolone and their sulfates.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F04%3A00011704" target="_blank" >RIV/00023761:_____/04:00011704 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Synthesis of (19-2H3)-analogs of dehydroepiandrosterone and pregnanolone and their sulfates.

Original language description

Deuterated analogs of pregnenolone and pregnenolone sulfate with three atoms of deuterium in position 19 were prepared. The synthetic approach was developed on derivatives of dehydroepiandrosterone, where initial intermediates were well characterized, and then applied to the pregnenolone series.

Czech name

Syntéza (19-2H3)-analogů dehydroepiandrosteronu a pregnenolonu a jejich sulfátů.

Czech description

Originální metodikou byly syntetizovány deuterované analogy DHEA a pregnenolonu využitelné jako tracery v biochemických experimentech i jako standardy pro analýzu GC-MC.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

<a href="/en/project/GA203%2F02%2F1440" target="_blank" >GA203/02/1440: Syntheses of neurosteroid sulfates labeled with deuterium and their monitoring in human brain tumor cells</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2004

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Steroids

ISSN

0039-128X

e-ISSN

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Volume of the periodical

69

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

161-171

UT code for WoS article

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EID of the result in the Scopus database

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